9,766 results found
    1. Ecology
    2. Evolutionary Biology

    Spatiotemporal ecological chaos enables gradual evolutionary diversification without niches or tradeoffs

    Aditya Mahadevan, Michael T Pearce, Daniel S Fisher
    Evolution of multiple closely related strains with host-pathogen-like interactions but only one niche and no tradeoffs, can give rise to a spatiotemporally chaotic ecological state that continually diversifies even with generalist mutations that slow the evolution.
    1. Neuroscience

    Value construction through sequential sampling explains serial dependencies in decision making

    Ariel Zylberberg, Akram Bakkour ... Michael N Shadlen
    The subjective value of choice options changes during deliberation, and accounting for these changes improves predictions of choices, response times, and BOLD fMRI activity.
    1. Computational and Systems Biology

    Neural arbitration between social and individual learning systems

    Andreea Oliviana Diaconescu, Madeline Stecy ... Philippe N Tobler
    Arbitration is formalised as the relative precision of predictions afforded by reward and social learning systems and is represented in modality-specific dopaminergic and dopaminoceptive regions, including the midbrain and amygdala.
    1. Neuroscience

    The rate of transient beta frequency events predicts behavior across tasks and species

    Hyeyoung Shin, Robert Law ... Stephanie R Jones
    Across species, tasks and recording modalities, the rate of transient neocortical beta frequency (15-29Hz) events strongly predicts perceptual ability, providing fundamental mechanistic insight, with implications for tracking and manipulating brain dynamics.
    1. Physics of Living Systems

    The younger flagellum sets the beat for Chlamydomonas reinhardtii

    Da Wei, Greta Quaranta ... Daniel SW Tam
    External hydrodynamic forcing on each flagellum of Chlamydomonas reinhardtii reveals a leader-follower relation between the two flagella in the synchronous beating.
    1. Ecology

    New Caledonian crows keep ‘valuable’ hooked tools safer than basic non-hooked tools

    Barbara C Klump, James JH St Clair, Christian Rutz
    Animals’ tool-handling behaviour can be used to make inferences about the value they ascribe to different tool types, unlocking considerable research potential for observational and experimental studies across diverse species.
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    A translation proofreader of archaeal origin imparts multi-aldehyde stress tolerance to land plants

    Pradeep Kumar, Ankit Roy ... Rajan Sankaranarayanan
    Genetic, biochemical, and bioinformatic analyses reveal how expanding metabolic repertoire interferes with fundamental processes like protein synthesis inside cells and the role of D-aminoacyl-tRNA deacylase2 in protecting these processes during terrestrialisation.
    1. Biochemistry and Chemical Biology

    Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site

    Rajendra Uprety, Tao Che ... Susruta Majumdar
    The structure-based design established a new approach to control pathway-selective activation of opioid receptors, resulting in new dual MOR/KOR G-protein biased agonist analgesics with attenuated liabilities.
    1. Structural Biology and Molecular Biophysics

    Structure and dynamics of a nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations

    Tone Bengtsen, Viktor L Holm ... Kresten Lindorff-Larsen
    Molecular simulations, small-angle X-ray and neutron scattering experiments and previously measured NMR experiments were combined to study the structure and dynamics of the proteins and lipids in a nanodisc.
    1. Neuroscience

    The severity of microstrokes depends on local vascular topology and baseline perfusion

    Franca Schmid, Giulia Conti ... Bruno Weber
    The number of inflows and outflows at the occluded capillary governs the local flow reduction, and the different topological configurations are probably designed for distinct functional tasks.

Refine your results by:

Type
Research categories