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    1. Microbiology and Infectious Disease

    Active invasion of bacteria into living fungal cells

    Nadine Moebius, Zerrin Üzüm ... Christian Hertweck
    Bacteria invade living fungal cells using secreted chitinolytic enzymes that allow for a traceless entry, as shown by microscopic snapshots.
    1. Developmental Biology
    2. Neuroscience

    Regulation of retinal axon growth by secreted Vax1 homeodomain protein

    Namsuk Kim, Kwang Wook Min ... Jin Woo Kim
    Secreted Vax1 homeodomain protein supports the development of optic chiasm by directly acting at the retinal ganglion cell axon.
    1. Physics of Living Systems
    2. Cell Biology

    Phase transitions of multivalent proteins can promote clustering of membrane receptors

    Sudeep Banjade, Michael K Rosen
    A new and general mechanism describes the organization of membrane proteins and their cytoplasmic ligands into micrometer-scale clusters, based on polymerization and concomitant phase separation of multivalent proteins.
    1. Cell Biology
    2. Developmental Biology

    LINKIN, a new transmembrane protein necessary for cell adhesion

    Mihoko Kato, Tsui-Fen Chou ... Paul W Sternberg
    LINKIN and three of its interactors-RUVBL1, RUVBL2, and α-tubulin-are required for cells to migrate together during organogenesis.
    1. Cell Biology

    Mapping the dynamics of force transduction at cell–cell junctions of epithelial clusters

    Mei Rosa Ng, Achim Besser ... Gaudenz Danuser
    The integrated quantification of spontaneous dynamic cell-cell force transmissions at both multi-cellular and subcellular scales enables spatiotemporal correlations of stress distribution with biomolecules in small cell clusters.
    1. Stem Cells and Regenerative Medicine

    Tissue Engineering: Muscling in on the third dimension

    Mohsen Afshar Bakooshli, Penney M Gilbert
    Version of Record
    Insight
    1. Developmental Biology
    2. Genetics and Genomics

    Systematic imaging reveals features and changing localization of mRNAs in Drosophila development

    Helena Jambor, Vineeth Surendranath ... Pavel Tomancak
    Genome wide analysis reveals that many transcripts are localized in cells of the ovary and that the localization status of mRNAs changes over time and in different cell types.
    1. Neuroscience

    The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion

    Peter Soba, Chun Han ... Yuh Nung Jan
    A cell surface receptor called Ret enables neurons to establish and maintain the organized arrays of dendrites that support communication between neurons.
    1. Cell Biology
    2. Developmental Biology

    FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis

    Melissa Kelley, John Yochem ... David S Fay
    A fibrillin-related protein, FBN-1, is a key component of the apical extracellular matrix and prevents epidermal cell deformation by biomechanical forces during morphogenesis of the C. elegans embryo.
    1. Developmental Biology

    A structure-based extracellular matrix expansion mechanism of fibrous tissue growth

    Nicholas S Kalson, Yinhui Lu ... Karl E Kadler
    Tendon fibroblast cells lay down a collagen matrix template during embryogenesis, and the expansion of this matrix drives post-natal tissue growth.