The spatial organization of pathogenic bacteria into microcolonies can be shaped by the stiffness of the substrate that they colonize, via modifications of the bacterial motility.
In vitro grown human muscle fibers display remarkable self-organisation capacities at the tissue, cellular, and molecular levels that are coordinated by mechanical tension.
Amélie Luise Godeau, Marco Leoni ... Daniel Riveline
A phase shift between local contractions drives 3D cell motility in experiments and in model or how a finite area in the dipole-quadrupole space explains cell motion with zero total force.
Louise Tzung-Harn Hsieh, Belinda S Hall ... Rachel E Simmonds
The secreted toxin mycolactone has severe effects on the cells lining blood vessels that will play a critical role in the development of swelling in Buruli ulcer disease.
Inhibition of ITGA2-mediated cancer cell-collagen interaction or targeting focal adhesion kinase activity may present an opportunity for therapeutic intervention of metastatic spread in ovarian cancer.
Zeinab Rekad, Michaël Ruff ... Ellen Van Obberghen-Schilling
Distinct and direct functions of the RNA binding protein SAM68 regulate integrin signaling and focal adhesion dynamics that condition basement membrane deposition and angiogenic behavior of endothelial cells.
