Our work demonstrated that eye opening differentially modulates inhibitory synaptic transmission from Sst-INs and FS-INs to excitatory neurons in the mammalian cortex.

The circadian clock in the model plant organism Arabidopsis thaliana is best described as a highly connected network made up of clock-regulated activators and repressors of transcription, rather than two coupled, repressor-based feedback loops.

Correlating changes in structure and gene expression in cone photoreceptors of mice daily, between birth and eye opening, created a resource that supports research in photoreceptor function, development, transplantation and repair.

Retrosplenial axons arriving in the parahippocampal region around the first day after birth are topographically organized, similarly to what has been reported in the adult.

The absence of functional inhibition is a developmentally transient circuit property of corticothalamic feedback that is essential for the central transmission of spontaneous retinal waves.

The development of neural responses proceeds through both the expansion and contraction of receptive field structure, and in addition depends upon changes in excitability of individual cells.

Establishing retinal contrast transmission as a novel determinant of mammalian fitness, this research adds functional significance to a prominent exception of nuclear organization, previously described in nocturnal rod photoreceptor cells.

A potassium channel, as a nonconducting function, organizes compartmentalized neuronal calcium signaling microdomains via structural and functional coupling of plasma membrane and endoplasmic reticulum calcium channels.

Evolutionary reduction in tissue number involves the simplification of the seaming process but not signaling during epithelial fusion.

The pressure of fluid in the inner ear is controlled by opening of cellular valves in the endolymphatic sac to allow for regulated transepithelial fluid flow.