751 results found
    1. Neuroscience

    Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves

    Miriam Schwalm et al.
    Locally recorded calcium events related to slow wave activity show a global cortical fMRI BOLD correlate, establishing a direct relation between a basic neurophysiological signal and the macroscopic perspective of pre-clinical fMRI.
    1. Cancer Biology

    Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice

    Shun Kishimoto et al.
    Using noise suppression, real-time imaging of glucose metabolism is possible by 13C MRI and reveals previously undetected metabolic differences within tumors.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences

    Raeann Goering et al.
    The molecular determinants for neuronal subcellular RNA transport by FMRP are defined, with interactions between RNA G-quadruplexes and the RGG domain of FMRP being of critical importance.
    1. Neuroscience

    Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI

    Martina Absinta et al.
    Meningeal lymphatic vessels are present in human and nonhuman primates (common marmoset monkeys) and they can be noninvasively imaged and mapped in vivo with high-resolution, clinical MRI.
    1. Neuroscience

    A critical re-evaluation of fMRI signatures of motor sequence learning

    Eva Berlot et al.
    A systematic assessment of previously proposed fMRI metrics of motor sequence learning reveals widespread activity reductions and subtle multivariate pattern changes outside of primary motor cortex.
    1. Neuroscience

    Using an achiasmic human visual system to quantify the relationship between the fMRI BOLD signal and neural response

    Pinglei Bao et al.
    The lower-level retinotopic visual cortex of humans born without the optic chiasm comprises two independent neuronal populations and forms a versatile model for quantifying the relationship between the fMRI BOLD signal and neural response.
    1. Neuroscience

    FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory

    Kirsty Sawicka et al.
    Identifying FMRP-bound mRNAs in hippocampal CA1 pyramidal neurons reveals cell-type specific regulation of autism-candidate and circadian mRNAs and FMRP-mediated control of memory across the circadian cycle.
    1. Neuroscience

    Mapping the human subcortical auditory system using histology, postmortem MRI and in vivo MRI at 7T

    Kevin R Sitek et al.
    MRI methods are promising techniques for investigating the human subcortical auditory system, and these publicly available data, atlases, and tools make researching human audition simpler and more reliable.
    1. Neuroscience

    Noninvasive quantification of axon radii using diffusion MRI

    Jelle Veraart et al.
    Cell-specific architectural properties such as the axon diameter of the white matter of the human brain can be quantified accurately and non-invasively using diffusion magnetic resonance imaging.
    1. Neuroscience

    Model-based fMRI reveals dissimilarity processes underlying base rate neglect

    Sean R O'Bryan et al.
    Model-based imaging shows that the rostrolateral prefrontal cortex supports dissimilarity-based heuristics that people may use when they are confronted with ambiguous scenarios.

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