Fast-spiking interneurons of the dorsolateral striatum are found to provide a microcircuit mechanism driving the circuit properties and behavioral adaptations that characterize habit.

Serotonin changes passive membrane properties in prefrontal fast-spiking interneurons to affect not only neuronal excitability but also the temporal filtering of synaptic inputs with a preference for gamma-frequency summation.

Analysis of AnkyrinR conditional knockout mice shows that AnkyrinR regulates PV+ fast-spiking interneurons by organizing and maintaining perineuronal nets and through the membrane clustering of Kv3.1b K⁺ channels.

Truncated Disrupted-in-schizophrenia 1 (Disc 1) ablates signaling of parvalbumin-expressing interneurons in the prefrontal cortex and underlies depression-related behaviour in mice.

An excess of novel non-canonical subtypes of parvalbumin+ interneurons in a mouse model of classical lissencephaly, which possess non-fast-spiking physiological properties, may contribute to network hyperexcitability common in this model.

The joint combination of interbranch distance and local caliber is sufficient to predict with high accuracy the distribution of myelin internodes along individual axons of neocortical GABAergic interneurons.

Cortical interneurons inhibit pyramidal cells to a greater degree when they form synapses with the pyramidal cell body than when they form synapses with dendrites.

A-type potassium conductances influence the distinctive firing behaviour of irregular-spiking interneurons.

Our work demonstrated that eye opening differentially modulates inhibitory synaptic transmission from Sst-INs and FS-INs to excitatory neurons in the mammalian cortex.

Biologically plausible changes in the excitabilities of single neurons may suffice to selectively modulate sequential network dynamics, without modifying of recurrent connectivity.