203 results found
    1. Structural Biology and Molecular Biophysics

    Protein denaturation at the air-water interface and how to prevent it

    Edoardo D'Imprima et al.
    Hydrophilized graphene prevents protein denaturation at the air-water interface.
    1. Neuroscience

    CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes

    Penelope Dimas et al.
    Endogenous synthesis of fatty acids by oligodendrocytes is essential for development and repair in the central nervous system.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Drosophila STING protein has a role in lipid metabolism

    Katarina Akhmetova et al.
    Drosophila STING protein, or stimulator of interferon genes, has a direct but previously unknown role in the lipid metabolism.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Isolation and transcriptomic analysis of Anopheles gambiae oenocytes enables the delineation of hydrocarbon biosynthesis

    Linda Grigoraki et al.
    Delineation of the cuticular hydrocarbon biosynthetic pathway in malaria vectors is a key step in understanding how mosquitoes adapt to anthropogenic change and vector control interventions.
    1. Evolutionary Biology

    Convergent changes in muscle metabolism depend on duration of high-altitude ancestry across Andean waterfowl

    Neal J Dawson et al.
    Changes in pathways of lipid oxidation, glycolysis, and mitochondrial oxidative phosphorylation are common strategies to cope with high-altitude hypoxia, but some changes require longer evolutionary time to arise.
    1. Biochemistry and Chemical Biology

    Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides

    Matthijs Kol et al.
    Photoswitchable ceramides containing an azobenzene photoswitch behave as light-controllable substrates for both sphingomyelin synthase and glucosylceramide synthase.
    1. Ecology
    2. Microbiology and Infectious Disease

    A novel ATP dependent dimethylsulfoniopropionate lyase in bacteria that releases dimethyl sulfide and acryloyl-CoA

    Chun-Yang Li et al.
    A novel dimethylsulfoniopropionate lyase was identified, which catalyzes dimethyl sulfide releasing by a new mechanism and is found in several bacterial lineages, revealing its important roles in global sulfur cycling.
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Evolution of a plant gene cluster in Solanaceae and emergence of metabolic diversity

    Pengxiang Fan et al.
    A nightshade family gene cluster creates phenotypic novelty in trichome defensive metabolites via evolution of lipid metabolic enzymes.
    1. Genetics and Genomics

    Genetic architecture of natural variation in cuticular hydrocarbon composition in Drosophila melanogaster

    Lauren M Dembeck et al.
    Genome wide association analyses in a wild-derived Drosophila melanogaster population uncover extensive variation in cuticular hydrocarbon composition, which may present a target for natural selection and adaptive evolution.
    1. Structural Biology and Molecular Biophysics

    Sequence co-evolution gives 3D contacts and structures of protein complexes

    Thomas A Hopf et al.
    Interactions in protein complexes can be predicted from evolutionary information from genomic sequences.

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