5,689 results found
    1. Neuroscience

    Visual projection neurons in the Drosophila lobula link feature detection to distinct behavioral programs

    Ming Wu et al.
    Neurons called lobula columnar cells help fruit flies respond appropriately to specific visual cues, such as those signaling an approaching predator.
    1. Neuroscience

    Visual Behavior: The eyes have it

    Mehmet Keleş, Mark A Frye
    Molecular genetic experiments are revealing how the fly brain generates behavioral responses to visual stimuli.
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    1. Computational and Systems Biology
    2. Genetics and Genomics

    Proteome-wide signatures of function in highly diverged intrinsically disordered regions

    Taraneh Zarin et al.
    Widespread, rapidly evolving disordered regions contain molecular features that are preserved over evolution and are associated with specific biological functions.
    1. Neuroscience

    An excitatory amacrine cell detects object motion and provides feature-selective input to ganglion cells in the mouse retina

    Tahnbee Kim et al.
    The mouse visual system is able to detect small moving objects due to the activity of VG3-amacrine cells, an unusual type of modulatory cell that uses the transmitter glutamate to activate retinal output cells.
    1. Cell Biology
    2. Evolutionary Biology

    Phylogenetic divergence of cell biological features

    Michael Lynch
    Cell biological features are subject to stochastic forces of mutation and random genetic drift, which together cause lineages exposed to identical selection pressures to diverge, and mean phenotypes to deviate from expectations under optimizing selection.
    1. Human Biology and Medicine

    Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis

    Jasmine C Wong et al.
    Immature hematopoietic cells from mice with a large segmental deletion found in human myeloid malignancies exhibit cardinal features of myelodysplastic syndrome.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Host proteostasis modulates influenza evolution

    Angela M Phillips et al.
    Host protein homeostasis is a critical force shaping influenza evolution, impacting both the nature of selection on the influenza genome and the accessibility of specific mutational trajectories.
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