Grant applications submitted to the NIH by African-American/Black PIs are less likely to be funded than applications from white PIs, and the NIH must find a solution that eliminates this racial disparity.

Blinding the initial review of applications for Beckman Young Investigator awards reduces prestige bias, but has no impact on the success rates for different genders.

White principal investigators applying to the National Science Foundation are consistently funded at higher rates than most non-white PIs.

The biomedical research enterprise in the US has become unsustainable and urgent action is needed to address a variety of problems.

A more balanced distribution of NIH grant funding among investigators would strengthen the diversity of the research enterprise, increase the likelihood of scientific breakthroughs, and lead to a greater return on taxpayers' investments.

Brazil would benefit from a long-term strategy for science and innovation that improves the standing of both science and scientists in the country.

Biomedical research in the US will become unsustainable unless scientists and research institutions start to question certain assumptions they have long taken for granted.

A cross-campus, cross-career stage and cross-disciplinary series of discussions at a large public university has produced a series of recommendations for addressing the problems confronting the biomedical research community in the US.

Members of UAW 5810—the union for postdoctoral researchers at the University of California—describe how their union has led to improved terms and conditions for postdocs.

Integrating mobile service and fine-granular sample data enhances SARS-CoV-2 genomic surveillance, improving variant tracking, optimizing efficiency, and guiding targeted sampling strategies.