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    1. Neuroscience

    Task-dependent coarticulation of movement sequences

    Hari Teja Kalidindi, Frederic Crevecoeur
    Long-latency reflexes flexibly encode future goals during sequential reaching movements, reflecting the parallel and task-dependent processing of a sequence of goals in circuits that mediate fast feedback control.
    1. Neuroscience

    Extrinsic and intrinsic dynamics in movement intermittency

    Damar Susilaradeya, Wei Xu ... Andrew Jackson
    The rhythmicity in upper-limb tracking movements and associated population dynamics in primary motor cortex is explained by a feedback controller incorporating optimal state estimation.
    1. Neuroscience

    Influence of sensory modality and control dynamics on human path integration

    Akis Stavropoulos, Kaushik J Lakshminarasimhan ... Dora E Angelaki
    Human path integration accuracy is strongly influenced by the underlying control dynamics, but less so when visual, rather than vestibular, feedback is available.
    1. Cell Biology

    Homeostatic control of START through negative feedback between Cln3-Cdk1 and Rim15/Greatwall kinase in budding yeast

    Nicolas Talarek, Elisabeth Gueydon, Etienne Schwob
    Inhibition of phosphatases by kinases develops Whi5 phosphorylation and cell cycle function in low cyclin-dependent kinase activity.
    1. Neuroscience

    Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

    Michelle M Frank, Austen A Sitko ... Lisa V Goodrich
    Single-nucleus sequencing, anatomy, and physiology reveal heterogeneity among olivocochlear neurons (a group of cells that provide feedback to the inner ear), identify a neuropeptide-enriched subtype, and show that neuropeptide expression changes during postnatal development and after sound exposure.
    1. Computational and Systems Biology
    2. Neuroscience

    Motor Control: Sensory feedback can give rise to neural rotations

    Omid G Sani, Maryam M Shanechi
    Investigating how an artificial network of neurons controls a simulated arm suggests that rotational patterns of activity in the motor cortex may rely on sensory feedback from the moving limb.
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    1. Neuroscience

    Corticofugal regulation of predictive coding

    Alexandria MH Lesicko, Christopher F Angeloni ... Maria N Geffen
    A specific neuronal pathway within the auditory system represents information about the statistical prediction and error for incoming sounds, thereby contributing to efficient representation of complex sounds and sound streams in the brain.
    1. Neuroscience

    Behavioral evidence for nested central pattern generator control of Drosophila grooming

    Primoz Ravbar, Neil Zhang, Julie H Simpson
    Complex motor behaviors can be assembled from simpler repeating elements controlled by pattern-generation circuits operating at different time scales.
    1. Developmental Biology
    2. Physics of Living Systems

    Cellular compartmentalisation and receptor promiscuity as a strategy for accurate and robust inference of position during morphogenesis

    Krishnan S Iyer, Chaitra Prabhakara ... Madan Rao
    An information theoretic and systems biology approach shows that cellular compartmentalisation and receptor promiscuity can facilitate the accurate and robust inference of position from noisy morphogen profiles, verified by experiments in Drosophila wing imaginal disc.
    1. Developmental Biology
    2. Genetics and Genomics

    Feedback between a retinoid-related nuclear receptor and the let-7 microRNAs controls the pace and number of molting cycles in C. elegans

    Ruhi Patel, Himani Galagali ... Alison R Frand
    A genetic oscillator composed of NHR-23 and let-7 family of microRNAs links the molting cycle timer and the heterochronic pathway to regulate the pace of molting in C. elegans and ensure that worms molt only four times.