1,949 results found
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Extracellular electron transfer increases fermentation in lactic acid bacteria via a hybrid metabolism

    Sara Tejedor-Sanz, Eric T Stevens ... Maria L Marco
    Lactic acid bacteria engage a hybrid metabolism which blends features of fermentation and respiration when they perform extracellular electron transfer.
    1. Computational and Systems Biology
    2. Developmental Biology

    Odd-paired controls frequency doubling in Drosophila segmentation by altering the pair-rule gene regulatory network

    Erik Clark, Michael Akam
    The organisation of the Drosophila embryo into segmental units is orchestrated by combinatorial regulatory interactions between spatially patterned and temporally patterned transcription factors.
    1. Developmental Biology

    Cell-autonomous timing drives the vertebrate segmentation clock’s wave pattern

    Laurel A Rohde, Arianne Bercowsky-Rama ... Andrew C Oates
    A noisy cell-intrinsic timer provides positional information for the segmentation clock, modulated by extrinsic factors such as FGF.
    1. Evolutionary Biology
    2. Neuroscience

    Mice and primates use distinct strategies for visual segmentation

    Francisco J Luongo, Lu Liu ... Doris Y Tsao
    The behavioral ability of mice and treeshrews to detect visual figures is highly texture dependent, unlike that of primates including macaques and mouse lemurs, and neural responses to figures in mouse visual cortex are similarly texture dependent.
    1. Epidemiology and Global Health

    A case study for a psychographic-behavioral segmentation approach for targeted demand generation in voluntary medical male circumcision

    Sema K Sgaier, Maria Eletskaya ... Steve Kretschmer
    A novel, hybrid segmentation technique reveals human heterogeneity in barriers towards a behavior, and is applied to characterize distinct segments in voluntary medical male circumcision.
    1. Genetics and Genomics

    Evidence for loss and reacquisition of alcoholic fermentation in a fructophilic yeast lineage

    Carla Gonçalves, Jennifer H Wisecaver ... Paula Gonçalves
    Comparative genomics coupled with genetic and biochemical studies show that central carbon metabolism in fungi can be remodeled by genes originating from bacteria.
    1. Plant Biology

    Accurate and versatile 3D segmentation of plant tissues at cellular resolution

    Adrian Wolny, Lorenzo Cerrone ... Anna Kreshuk
    Convolutional neural networks and graph partitioning algorithms can be combined into an easy-to-use tool for segmentation of cells in dense plant tissue volumes imaged with light microscopy.
    1. Structural Biology and Molecular Biophysics

    Streamlining segmentation of cryo-electron tomography datasets with Ais

    Mart GF Last, Leoni Abendstein ... Thomas H Sharp
    The software package Ais simplifies automated segmentation in cryo-electron tomography, enabling users to segment, detect particles, and visualize data in a streamlined and accessible workflow.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Transition between fermentation and respiration determines history-dependent behavior in fluctuating carbon sources

    Bram Cerulus, Abbas Jariani ... Kevin J Verstrepen
    Live-cell microscopy and genome-wide screens reveal how slow transitions in metabolism can underlie metabolic memory, providing a model for organisms demonstrating similar history-dependent behaviour and routes to improve industrial microbes.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Zygotic pioneer factor activity of Odd-paired/Zic is necessary for late function of the Drosophila segmentation network

    Isabella V Soluri, Lauren M Zumerling ... Shelby A Blythe
    Mechanisms for shaping the chromatin accessibility landscape operate during development to regulate how embryonic patterning information is interpreted at the level of gene regulatory networks.

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