Fibrinogen, a key protein involved in blood coagulation, contains a disordered and previously poorly characterised region called αC that plays a critical role in fibrin fibre growth and clot stability.

Bacterial-encoded covalent adhesion is a new molecular principle in host-microbe interactions and may play a key role in host colonization by a wide range of Gram-positive bacteria.

Ligand binding, force and chemistry combine to control the function of a cell surface receptor.

The use of liquid-infused catheters results in significant reduction of bladder and catheter colonization, systemic dissemination, and bladder inflammation in a clinically relevant mouse model of CAUTI by targeting host-protein deposition on the urinary catheter.

Longitudinal laboratory testing results tied to SARS-CoV-2 diagnostic PCR results of more than 2500 patients reveal the temporal evolution of COVID-associated coagulopathy.

For severe COVID-19 patients' red blood cells, healthy donor plasma reduces pathological red blood cell shape alterations and improves microcapillary flow in vitro through an interaction between red blood cells and plasma.

The fibronectin synergy site is only required in vivo when forces exceed or αvβ3 integrin levels fall below certain thresholds.

Heparan sulfates in the vessel wall bind and regulate signaling from the megakaryocyte/platelet-specific inhibitory receptor G6b-B, a critical regulator of platelet homeostasis.

A novel bioengineered human skeletal muscle model with accurate physiological and pharmacological responses may provide a useful tool for preclinical testing.