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    1. Immunology and Inflammation

    Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation

    Atiqur Rahman, Katherine M Henry ... Lynne R Prince
    Targeting ErbB receptor tyrosine kinases modifies neutrophil survival and inflammation across multiple species, and reveals a new use for ErbB therapeutics in resolving inflammatory disease.
    1. Neuroscience

    A primal role for the vestibular sense in the development of coordinated locomotion

    David E Ehrlich, David Schoppik
    Zebrafish use their sense of gravity and their cerebellum to coordinate the fin and body movements that, as they develop, allow them to better maintain balance as they climb.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    The transcriptional landscape underlying larval development and metamorphosis in the Malabar grouper (Epinephelus malabaricus)

    Roger Huerlimann, Natacha Roux ... Timothy Ravasi
    Transcriptomic analyses of Malabar grouper show pathways known to be involved in metamorphosis are also upregulated at an early stage of larval development, suggesting an additional function during early development.
    1. Cell Biology
    2. Genetics and Genomics

    Matriptase activation of Gq drives epithelial disruption and inflammation via RSK and DUOX

    Jiajia Ma, Claire A Scott ... Tom J Carney
    The serine protease Matriptase orchestrates simultaneous epithelial cell motility and inflammation in pathological states through respective activation of the MAPK pathway and generation of hydrogen peroxide.
    1. Cell Biology
    2. Developmental Biology

    Zebrafish fin regeneration involves generic and regeneration-specific osteoblast injury responses

    Ivonne Sehring, Hossein Falah Mohammadi ... Gilbert Weidinger
    Osteoblast dedifferentiation and migration are injury responses that are differentially regulated and independent of regenerative bone formation.
    1. Cell Biology
    2. Evolutionary Biology

    Lipid droplet biology and evolution illuminated by the characterization of a novel perilipin in teleost fish

    James G Granneman, Vickie A Kimler ... Ryan Thummel
    Phylogenetic, biochemical, and genetic techniques reveal a novel and ancient member of the Perilipin family, termed Plin6, that functions to concentrate and traffic lipophilic skin pigment in teleost fish.
    1. Ecology
    2. Evolutionary Biology

    Fin whale song evolution in the North Atlantic

    Miriam Romagosa, Sharon Nieukirk ... Mónica A Silva
    The rapid and gradual fin whale songs changes adopted by individuals of a certain area provide evidence of vocal learning in this species, elucidate patterns of song evolution and hints on the limits of song variation.
    1. Stem Cells and Regenerative Medicine
    2. Chromosomes and Gene Expression

    The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration

    Robert G Hesse, Gayle K Kouklis ... Jason H Pomerantz
    Evolution of tumor suppressor genes can involve a trade-off because the acquisition of certain anti-cancer characteristics diminishes the ability to regenerate damaged tissue.
    1. Developmental Biology

    Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes

    Laura E Kuil, Nynke Oosterhof ... Tjakko J van Ham
    Embryonic and definitive macrophages require colony-stimulating factor 1 receptor, whereas non-hematopoietic metaphocytes that resemble macrophages do not, explaining the relative high numbers of putative macrophages in Csf1r-deficient zebrafish.
    1. Developmental Biology

    Development and genetics of red coloration in the zebrafish relative Danio albolineatus

    Delai Huang, Victor M Lewis ... David M Parichy
    In the zebrafish relative Danio albolineatus, red erythrophores share a common progenitor with yellow xanthophores and require Cyp2ae2 and Bdh1a for accumulation of red ketocarotenoid pigment.