A hydrodynamic model of fish swimming in a channel predicts a critical flow speed for fish to successfully swim against a flow, unveiling a passive mechanism for rheotaxis to emerge without access to any sensory information.
Sophia Karpenko, Sebastien Wolf ... Georges Debrégeas
Light-seeking strategies in Zebrafish larvae are dissected using a virtual-reality assay, and these data are used to establish minimal stochastic and neural-circuits models that quantitatively capture this behavior.
The mathematical model incorporating new parameters explains multimodal distributions in escape direction (i.e., multiple preferred escape trajectories), which are previously observed in various animal taxa.
Peter Ahorukomeye, Maria M Disotuar ... Helena Safavi-Hemami
The unique modus operandi of cone snail venom insulins provides new insight into insulin receptor activation and informs on the design of insulin analogs for the treatment of diabetes.
Beth M Stadtmueller, Kathryn E Huey-Tubman ... Pamela J Bjorkman
The ectodomain of the human polymeric Ig receptor maintains a closed triangular shape that binds and excludes bacteria in mucosa, or opens to bind and transport polymeric Ig ligands across epithelial cells.
Analysis and modeling of group behavior of adult zebrafish shows that a specialized social interaction mechanism increases foraging efficiency and equality within groups, under a variety of environmental conditions.
In vivo recordings and computational modeling of the electrosensory lobe of mormyrid fish provide a circuit-level description of how learning generalizes to new situations.
Hadeel Alyenbaawi, Richard Kanyo ... W Ted Allison
A traumatic brain injury model is invented for larval zebrafish and applied to a new fluorescent 'tauopathy reporter fish', revealing a role for seizures in progression towards dementias.