962 results found
    1. Microbiology and Infectious Disease

    The Mla pathway in Acinetobacter baumannii has no demonstrable role in anterograde lipid transport

    Matthew J Powers et al.
    An outer membrane vesicle pulse-chase assay demonstrates that the Acinetobacter baumannii Mla system is a retrograde lipid transporter.
    1. Evolutionary Biology

    Convergent changes in muscle metabolism depend on duration of high-altitude ancestry across Andean waterfowl

    Neal J Dawson et al.
    Changes in pathways of lipid oxidation, glycolysis, and mitochondrial oxidative phosphorylation are common strategies to cope with high-altitude hypoxia, but some changes require longer evolutionary time to arise.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Clusters of polymorphic transmembrane genes control resistance to schistosomes in snail vectors

    Jacob A Tennessen et al.
    A region of the Biomphalaria genome, containing highly divergent haplotypes with different combinations of transmembrane genes, strongly impacts whether these snails can transmit parasitic schistosomes.
    1. Neuroscience

    Efficient sampling and noisy decisions

    Joseph A Heng et al.
    An efficient coding theory for higher-level cognitive processes reveals that humans efficiently adapt to contextual distributions by economizing on environmental prior information.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races

    Jeannette L Tenthorey et al.
    Mutations in the TRIM5α retrovirus-binding interface frequently improve but rarely disrupt retroviral restriction.
    1. Ecology
    2. Physics of Living Systems

    Nutrient levels and trade-offs control diversity in a serial dilution ecosystem

    Amir Erez et al.
    Whereas theories of ecological diversity mostly consider continuously supplied nutrients, a seasonal model uncovers a general mechanism that controls diversity and reconciles conflicting experimental findings.
    1. Developmental Biology
    2. Genetics and Genomics

    Speciation and the developmental alarm clock

    Asher D Cutter, Joanna D Bundus
    Integrating speciation genetics with ontogeny can identify predictable rules in the molecular evolution of developmental pathways and in the accumulation of reproductive isolation as genomes diverge.
    1. Genetics and Genomics

    A regulatory pathway that selectively up-regulates elongasome function in the absence of class A PBPs

    Yesha Patel et al.
    Balanced peptidoglycan synthesis requires regulators, including sigma-I and WalKR, that coordinate the diffusive action of class A PBPs and the directional motion of the MreB-directed elongasome.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Genomic architecture and evolutionary antagonism drive allelic expression bias in the social supergene of red fire ants

    Carlos Martinez-Ruiz et al.
    Analyses of allelic- and socially-biased gene expression reveal that suppressed recombination causes most of the expression differences in the social supergene, with only few differences due to socially antagonistic selection.

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