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    1. Cell Biology
    2. Developmental Biology

    The full length BEND2 protein is dispensable for spermatogenesis but required for setting the ovarian reserve in mice

    Yan Huang, Nina Bucevic ... Ignasi Roig
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics

    Deficiency in DNAH12 causes male infertility by impairing DNAH1 and DNALI1 recruitment in humans and mice

    Menglei Yang, Hafiz Muhammad Jafar Hussain ... Baolu Shi
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Evolutionary Biology

    The population genetics of convergent adaptation in maize and teosinte is not locally restricted

    Silas Tittes, Anne Lorant ... Jeffrey Ross-Ibarra
    Adaptation of domesticated maize and its wild relative teosinte has been facilitated by the geographically widespread exchange of beneficial alleles between them.
    1. Microbiology and Infectious Disease

    Quantification of Salmonella enterica serovar Typhimurium population dynamics in murine infection using a highly diverse barcoded library

    Julia A Hotinger, Ian W Campbell ... Matthew K Waldor
    Microbial lineage tracing during murine systemic infection with Salmonella uncovered the bottlenecks that restrict colonization and the hidden routes of interorgan dissemination that drive heterogeneity in infection outcomes.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    CryoEM structures of Kv1.2 potassium channels, conducting and non-conducting

    Yangyu Wu, Yangyang Yan ... Fred J Sigworth
    The well-studied Kv1.2 potassium ion channel is observed in a variety of states and conditions, to understand mechanisms of ion permeation, gating and block.
    1. Neuroscience

    Probing the role of synaptic adhesion molecule RTN4RL2 in setting up cochlear connectivity

    Nare Karagulyan, Maja Überegger ... Christine Bandtlow
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Synthetic gene circuits that selectively target RAS-driven cancers

    Gabriel Senn, Leon Nissen, Yaakov Benenson
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Enalapril mitigates aging by targeting antioxidative genes via phosphorylated Smad1/5/9

    Wencong Lyu, Haochen Wang ... Wei Tao
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete