mSTARR-seq identifies regions of the genome where DNA methylation causally impacts gene expression, providing a map of which epigenetic marks may influence trait variation.

Pseudogenization of rcsD alters canonical Rcs phosphorelay signalling and marks a significant adaptive evolutionary step in the emergence of ubiquitous extant branches of Yersinia pestis that can maintain stable plague outbreaks.

The structure of the Ana2 Central Coiled-Coil Domain provides insight into how centriolar cartwheel components may be recruited and assembled, and indicates that cartwheel assembly involves more than just SAS-6 oligomerisation.

Staphylococcal heme acquisition needs a highly structured cell envelope, the membrane transporter accumulates in membrane domains most likely to allow concerted passage of heme from the cell wall-funnel to the membrane.

Cell lineage tracing and biochemical analysis of cell fate during murine stem cell differentiation demonstrates a specific cooperativity between perturbations in histone methylation and eroded telomeres that destabilize cell differentiation.

Amino acid and sugar supplement induce appendage/limb regeneration in cnidarians, insects, and mammals.

Mathematical and experimental analyses suggest that despite their complex architectures, multiple metazoan signaling pathways act in physiological contexts as linear signal transmitters.

Advanced data analysis of molecular dynamics simulations of complex lipid membranes provides a quantitative and predictive model of the molecular features that control electroporation.

Analysis of protein content and protein composition of the ChAdOx1 nCov-19 vaccine, but not of the Ad26.COV2.S vaccine, indicated significantly higher than expected levels of host cell proteins (HCPs) and of free viral proteins.

Genetic susceptibility to an infectious disease is linked to competition for binding a molecule on the bacterial surface by two host proteins with opposing roles in host immunity.