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    1. Immunology and Inflammation

    Endothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesion

    Liang Gao et al.
    The cell surface protein CD95 mediates neutrophil slow rolling and adhesion during inflammation.
    1. Developmental Biology
    2. Neuroscience

    Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein

    Stephan Heermann et al.
    The lens-averted domains of the optic vesicle are reservoirs of neuroretinal cells that flow into the developing optic cup in a process that is critically influenced by BMP signaling.
    1. Cell Biology

    Receptors: How low can you go?

    H Steven Wiley
    Extremely low numbers of active epidermal growth factor receptors are sufficient to drive tumor growth.
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    1. Computational and Systems Biology
    2. Physics of Living Systems

    Imaging single-cell blood flow in the smallest to largest vessels in the living retina

    Aby Joseph et al.
    By using a specialized camera that corrects for eye blur, millions of single-blood-cells are imaged, and their speed measured, as they travel through the largest-to-smallest vessels of the retina.
    1. Human Biology and Medicine
    2. Neuroscience

    Propagated infra-slow intrinsic brain activity reorganizes across wake and slow wave sleep

    Anish Mitra et al.
    Human fMRI experiments reveal differences in the propagation of spontaneous brain activity during sleep versus wakefulness.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Multiple sources of slow activity fluctuations in a bacterial chemosensory network

    Remy Colin et al.
    Single-cell FRET measurements reveal large temporal activity fluctuations within this signaling pathway in Escherichia coli, caused by stochasticity of receptor methylation combined with allosteric interactions and slow rearrangements within receptor clusters.
    1. Physics of Living Systems
    2. Cell Biology

    Cortical flow aligns actin filaments to form a furrow

    Anne-Cecile Reymann et al.
    Compressing the actomyosin network by cortical flow causes filaments to align and form a constricting ring.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    Nuclear microenvironments modulate transcription from low-affinity enhancers

    Albert Tsai et al.
    Efficient transcription from low-affinity enhancers is driven by nuclear microenvironments of transcription factors.
    1. Genetics and Genomics
    2. Plant Biology

    Contesting the presence of wheat in the British Isles 8,000 years ago by assessing ancient DNA authenticity from low-coverage data

    Clemens L Weiß et al.
    A computational method to authenticate low-coverage ancient DNA experiments shows that putative wheat sequences from 8000 years old sediments are most likely not of ancient origin.
    1. Neuroscience

    IK1 channels do not contribute to the slow afterhyperpolarization in pyramidal neurons

    Kang Wang et al.
    The slow afterhyperpolarization that follows a burst of action potentials is a powerful regulator of neuronal excitability and is not due to IK1 (KCNN4), a member of the SK channel family.