Single-cell FRET measurements reveal large temporal activity fluctuations within this signaling pathway in Escherichia coli, caused by stochasticity of receptor methylation combined with allosteric interactions and slow rearrangements within receptor clusters.
A systematic comparison of experimentally measured and theoretically predicted magnitudes of organelle abundance fluctuations suggests that budding yeast produces the maximum level of variability in organelle abundance that can be generated by organelle biogenesis pathways.
Neuronal participation in generation of motor patterns in the spinal circuits is lognormal, which is an indication of a rich diversity of activity within the mean-driven as well as the fluctuation-driven regimes.
Cyanobacteria cope with both predictable day/night changes and natural fluctuations in light during the day by adjusting the expression dynamics of circadian-clock-controlled genes via a network of transcriptional regulators.
Live-cell microscopy and genome-wide screens reveal how slow transitions in metabolism can underlie metabolic memory, providing a model for organisms demonstrating similar history-dependent behaviour and routes to improve industrial microbes.