Lior Matityahu, Jeffrey M Malgady ... Joshua L Plotkin
A novel mechanism describes how tonic activation of nicotinic acetylcholine receptors can modulate the timing of striatal output by priming feedforward inhibition.
Suparna Ray, Miriam I Rosenberg ... François Payre
mille-pattes micropeptides have conserved function in insect embryonic patterning together with transcription factor Shaven-baby and ubiquitin ligase Ubr3, except in flies wherein restoring broad embryonic Svb expression restores patterning potency.
Laura E Mickelsen, William F Flynn ... Alexander C Jackson
Single cell RNA–sequencing and neuroanatomical methods reveal unexpected molecular diversity and highly segregated spatial organization of neuronal cell types within the mouse ventral posterior hypothalamus, including the mammillary nuclei.
Cardiovascular disease, the top cause of diabetic deaths, progresses via vascular endothelial dysfunction, with circHMGCS1 and miR4521 highlighted as potential markers for the development of this condition.
Alterations of DNA methylation were associated with articular cartilage degeneration in hemophilic arthropathy, and aberrant methylation and expression of TNXB promote blood-induced chondrocyte apoptosis by regulating AKT activation.
Postnatal KIF2A is a key regulator for axon/dendrite determination of developing dentate granule cells, and its loss developed apical axons in dentate molecular layer, broke hippocampal wiring, and induced temporal lobe epilepsy.
Mouse brain neurons response to transcranial ultrasound at the energy level of 5 mW/cm2 and repeated stimulations lead to neurogenesis while ASIC1a is required both in vitro and in vivo as one of the mechanoreceptors.
Cholecystokinin-positive neural projection from entorhinal cortex to lateral amygdala modulates the long-term potentiation of auditory-evoked potential in lateral amygdala and underlies the formation of trace fear memory.
