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Page 2 of 1,542
    1. Computational and Systems Biology
    2. Neuroscience

    Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice

    Romane Cecchi, Fabien Vinckier ... Julien Bastin
    Invasive electrophysiological recordings from the human brain reveal that different mood levels translate into different brain states that predispose subjects to make risky or safe decisions.
    1. Neuroscience

    The temporal representation of experience in subjective mood

    Hanna Keren, Charles Zheng ... Argyris Stringaris
    While current theories assume that mood is dominated by most recent experiences, computational modeling shows that mood is shaped by first experiences that carry a long-lasting overarching influence on mood.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Delayed antibiotic exposure induces population collapse in enterococcal communities with drug-resistant subpopulations

    Kelsey M Hallinen, Jason Karslake, Kevin B Wood
    Collapse of bacterial communities containing antibiotic-resistant and susceptible cells can be driven by increased population size or delayed drug exposure.
    1. Ecology
    2. Evolutionary Biology

    The African ape-like foot of Ardipithecus ramidus and its implications for the origin of bipedalism

    Thomas Cody Prang
    The most recent common ancestor of humans, chimpanzees, and bonobos possessed a foot adapted to terrestrial quadrupedalism and climbing.
    1. Developmental Biology
    2. Physics of Living Systems

    Controlling periodic long-range signalling to drive a morphogenetic transition

    Hugh Z Ford, Angelika Manhart, Jonathan R Chubb
    Cells control signal circulation to set the frequency of information transmitted over tissue scales.
    1. Neuroscience

    Synaptic mechanisms of top-down control in the non-lemniscal inferior colliculus

    Hannah M Oberle, Alexander N Ford ... Pierre F Apostolides
    Optogenetic and electrophysiological experiments show how a behaviorally relevant 'feedback' pathway from auditory cortex controls neural activity in the inferior colliculus, an auditory midbrain region important for processing complex time-varying sounds such as speech.
    1. Cancer Biology
    2. Computational and Systems Biology

    Identifying prostate cancer and its clinical risk in asymptomatic men using machine learning of high dimensional peripheral blood flow cytometric natural killer cell subset phenotyping data

    Simon P Hood, Georgina Cosma ... A Graham Pockley
    Diagnosing the presence and clinical significance of prostate cancer can be achieved using AI-based analysis of peripheral blood natural killer (NK) cell subset profiles.
    1. Cancer Biology

    MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs

    C David Wood, Hildegonda Veenstra ... Michelle J West
    Epstein-Barr virus controls B-cell growth and survival through large-scale reorganization of the enhancers of the MYC and BCL2L11 genes, and may promote MYC translocations as a result.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 Å resolution

    Xing Zhang, Huatao Guo ... Z Hong Zhou
    Cryo electron microscopy and structure-based mutagenesis reveal that the bacteriophage BPP-1 contains two of the three major recognized viral folds, one of which exhibits a new topology.
    1. Neuroscience

    Sex-specific resilience of neocortex to food restriction

    Zahid Padamsey, Danai Katsanevaki ... Nathalie L Rochefort
    Multi-scale analysis of mouse visual cortex reveals a sex-specific difference in response to long-term food restriction, with males being more impacted than females.