Valentina Baldazzi, Delphine Ropers ... Hidde de Jong
A coarse-grained model of microbial growth coupling fluxes of carbon and energy shows that resource allocation is a major explanatory factor of the observed variability of growth rates and growth yields across different bacterial strains.
Wilhelmina E van Riel, Ankit Rai ... Anna Akhmanova
Kinesin-4 KIF21B combines a processive motor activity with two non-motor microtubule-binding domains and an autoregulatory region to induce pausing of microtubule plus ends.
Artemis Koumoundourou, Märt Rannap ... Stefan Britsch
Molecular genetic, cell culture as well as electrophysiological analyses reveal a C1ql2/Neurexin3(25b+)-dependent molecular pathway through which Bcl11b controls critical functions of adult hippocampal mossy fiber synapses.
Robert J Tetley, Guy B Blanchard ... Bénédicte Sanson
Analysing Myosin II unipolar planar polarisation with high spatial and temporal resolution during Drosophila axis extension reveals how tissue boundaries drive polarized cell intercalation while limiting cell mixing.
Maria Katharina Eckstein, Sarah L Master ... Anne GE Collins
Context factors such as experimental task and model parameterization can significantly impact modeling results, such that across tasks, the same participants show different fitted parameter values, and parameters capture different cognitive processes across tasks.
Animals work in a world full of surprises, where using energy to position sensors proportional to the location's expected information avoids the pitfalls of positioning them at the information maxima.
Taylor B Updegrove, Jailynn Harke ... Kumaran S Ramamurthi
Reengineering the nucleotide-binding pocket of an extant ATPase to restore ancestral GTPase activity revealed an ATP-dependent intermediate required for function and suggested why the protein evolved to use ATP.