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    1. Chromosomes and Gene Expression

    Chromosome structure in Drosophila is determined by boundary pairing not loop extrusion

    Xinyang Bing, Wenfan Ke ... James B Jaynes
    Boundary:boundary pairing interactions drive TAD formation in Drosophila.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Should I stay or should I go? Spatio-temporal dynamics of bacterial biofilms in confined flows

    Massinissa Benbelkacem, Gabriel Ramos ... Yohan Davit
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Switch-like Arp2/3 activation upon WASP and WIP recruitment to an apparent threshold level by multivalent linker proteins in vivo

    Yidi Sun, Nicole T Leong ... David G Drubin
    Intersectin counterparts in yeast recruit WASP and WIP to endocytic sites to establish a robust multivalent SH3 domain-PRM interaction network which gives actin assembly onset a switch-like behavior in vivo.
    1. Cell Biology

    UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins

    Satoshi Ninagawa, Masaki Matsuo ... Kazutoshi Mori
    The fate of glycoproteins in the endoplasmic reticulum whether they are directed toward folding or targeted to degradation depends on a tug of war between UGGT1 and EDEM family proteins.
    1. Cell Biology

    Dual recognition of multiple signals in bacterial outer membrane proteins enhances assembly and maintains membrane integrity

    Edward M Germany, Nakajohn Thewasano ... Takuya Shiota
    Bacterial outer membrane proteins are recognized by BamD at specific signals located in multiple β-strands at the C-terminus of these proteins, and this recognition is important for efficient outer membrane protein assembly and maintaining the integrity of outer membrane.
    1. Biochemistry and Chemical Biology

    Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

    Gabriella O Estevam, Edmond M Linossi ... James S Fraser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Cntnap2 loss drives striatal neuron hyperexcitability and behavioral inflexibility

    Katherine R Cording, Emilie M Tu ... Helen S Bateup
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Ecology

    Echolocating toothed whales use ultra-fast echo-kinetic responses to track evasive prey

    Heather Vance, Peter T Madsen ... Mark Johnson
    Echolocating toothed whales can detect and react to sudden prey movements during close approaches with speeds similar to ultra-fast tracking responses in human vision.
    1. Neuroscience

    Location- and feature-based selection histories make independent, qualitatively distinct contributions to urgent visuomotor performance

    Emily E Oor, Emilio Salinas, Terrence R Stanford
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    A chromatic feature detector in the retina signals visual context changes

    Larissa Höfling, Klaudia P Szatko ... Thomas Euler
    A modelling-based analysis reveals a novel type of selectivity for chromatic contrast in a mouse retinal ganglion cell type, and experimental evidence shows that this feature makes this cell type well suited for detecting behaviourally relevant changes in visual context.