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    1. Neuroscience

    Episodic long-term memory formation during slow-wave sleep

    Flavio J Schmidig, Simon Ruch, Katharina Henke
    Sleep-encoded vocabulary influences awake decision-making 36 hr later, particularly when targeting the vocabulary to slow-wave troughs, which suggests that unconscious episodic memory formation during deep sleep is possible.
    1. Neuroscience

    Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates

    Shan Yu, Tiago L Ribeiro ... Dietmar Plenz
    Ongoing and stimulus-evoked brain activity in cortex are shown in nonhuman primates to follow the organization of neuronal avalanches, a core commonality that might guide optimal information processing in the brain.
    1. Neuroscience

    Phase-tuned neuronal firing encodes human contextual representations for navigational goals

    Andrew J Watrous, Jonathan Miller ... Joshua Jacobs
    Prospective navigational goals are represented by single neuron firing rates and firing relative to slow oscillatory phase (phase coding) in the human medial temporal lobe.
    1. Neuroscience

    Characterizing a psychiatric symptom dimension related to deficits in goal-directed control

    Claire M Gillan, Michal Kosinski ... Nathaniel D Daw
    A dimensional approach to psychiatry demonstrates the specificity and generalizability of a neurocognitive marker of compulsive behavior and intrusive thought via large-scale online testing.
    1. Neuroscience

    Attenuation of dopamine-modulated prefrontal value signals underlies probabilistic reward learning deficits in old age

    Lieke de Boer, Jan Axelsson ... Marc Guitart-Masip
    Attenuated anticipatory activity in ventromedial prefrontal cortex is modulated by dopamine D1 receptor density in nucleus accumbens, and accounts for impaired probabilistic reward learning in older adults.
    1. Neuroscience

    Pallidal neuromodulation of the explore/exploit trade-off in decision-making

    Ana Luisa de A Marcelino, Owen Gray ... Tom Gilbertson
    Deep brain stimulation (DBS) exhibit that the excitability of the basal ganglia can govern the trade off between exploiting available resources or exploring alternative courses of action.
    1. Neuroscience
    2. Physics of Living Systems

    Scale-free behavioral dynamics directly linked with scale-free cortical dynamics

    Sabrina A Jones, Jacob H Barfield ... Woodrow L Shew
    Complex, multi-scale natural behaviors may arise from subpopulations of neurons in cerebral cortex operating near the tipping point of a phase transition, that is, near criticality.
    1. Neuroscience

    Subthalamic, not striatal, activity correlates with basal ganglia downstream activity in normal and parkinsonian monkeys

    Marc Deffains, Liliya Iskhakova ... Hagai Bergman
    The spiking activity of the subthalamic nucleus, rather than the activity of striatal projection neurons, orchestrates basal ganglia downstream activity and output commands in health and Parkinson’s disease.
    1. Neuroscience

    Behavioural pharmacology predicts disrupted signalling pathways and candidate therapeutics from zebrafish mutants of Alzheimer’s disease risk genes

    François Kroll, Joshua Donnelly ... Jason Rihel
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    An open-source, high-performance tool for automated sleep staging

    Raphael Vallat, Matthew P Walker
    A robust automatic sleep-staging algorithm offers a high level of accuracy matching that of typical human interscorer agreement.