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    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural characterization of ribosome recruitment and translocation by type IV IRES

    Jason Murray et al.
    A Internal Ribosomal Entry Site RNA has been visualised by high resolution cryoEM, trapped in the ribosome in an intermediate state of translocation.
    1. Genetics and Genomics

    A large gene family in fission yeast encodes spore killers that subvert Mendel’s law

    Wen Hu et al.
    Two members of a large fission yeast (Schizosaccharomyces pombe) gene family are shown to act as spore killers that enhance their own transmission into progenies by impeding the maturation of spores not inheriting them.
    1. Biochemistry and Chemical Biology
    2. Physics of Living Systems

    Direct measurement of the mechanical work during translocation by the ribosome

    Tingting Liu et al.
    ‘Optical tweezers’ measurements of single ribosomes and single mRNA molecules show that the translation rate depends exponentially on the applied force, and suggests that the ribosome functions as a Brownian ratchet.
    1. Cell Biology

    Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized

    Danielle M Garshott et al.
    A hierarchical relationship among highly conserved regulatory ribosomal ubiquitylation events and the presence of antagonistic deubiquitylating enzymes suggests a dynamic ubiquitin code impacts ribosome-associated activities.