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Biochemistry and Chemical Biology
Physics of Living Systems
Direct measurement of the mechanical work during translocation by the ribosome
Tingting Liu et al.
‘Optical tweezers’ measurements of single ribosomes and single mRNA molecules show that the translation rate depends exponentially on the applied force, and suggests that the ribosome functions as a Brownian ratchet.
Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex
Marta Florio et al.
Transcriptomic and genomic analysis provides a resource of 50 primate-specific genes preferentially expressed in neural progenitors of fetal human neocortex, 15 of which are specific to humans.
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