Certain types of 3D chromatin loops are easy to predict from existing or easily obtainable 2D information, which benefits gene expression studies in tissues/cells/organisms without extensive pre-existing 3D information.

Dcp2 C-terminal domain cis-regulatory elements collaborating with specific activators control decapping enzyme targeting and activation by orchestrating sequential assembly of distinct decapping complexes.

Non-invasive disinhibition of the oculomotor system shows that ongoing preparatory activity in the superior colliculus has movement-generating potential and need not rise to threshold in order to produce a saccade.

Transcriptional regulation evolves at indistinguishable rates in mammals, birds and insect lineages despite large differences in underlying rates of sequence evolution.

A whole brain analysis using human neuroimaging data shows neural correlates of individual differences in conditioned fear.

An evolutionary algorithm is used to build gene networks implementing cell size control, and suggests multiple ways for evolution to first build sizers and turn them into adders depending on evolutionary constraints.

A novel dual genome approach that combines genetically diverse mice and a library of bacterial mutants to define the genome-wide host pathogen interactions that drive distinct outcomes to tuberculosis.

rDNA copy number is shown to dynamically change during aging and through generations, and is actively maintained in male germline of Drosophila.

Muscarinic antagonism is causally involved in motivation and incentivisation in healthy human participants, partially mediated via preparatory neural signatures, with implications for cholinergic treatment of Parkinson's disease.

The convergence of two visual pathways at the level of retinal bipolar cells accounts for key features of ganglion cell responses.