534 results found
    1. Neuroscience

    Nucleophile sensitivity of Drosophila TRPA1 underlies light-induced feeding deterrence

    Eun Jo Du et al.
    Electron-donating nucleophilic compounds activate TRPA1 ion channels in fruit flies and mosquitoes, but not humans, making TRPA1 a promising target for insect repellants.
    1. Developmental Biology
    2. Immunology and Inflammation

    Chemokines: The cell sets the tone

    Jonna Alanko, Michael Sixt
    In zebrafish larvae, it is the cell type that determines how the cell responds to a chemokine signal.
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    1. Developmental Biology

    The Natural History of Model Organisms: An organismal perspective on C. intestinalis development, origins and diversification

    Matthew J Kourakis, William C Smith
    The life cycle and morphology of the sea squirt Ciona intestinalis shed light on vertebrate evolution.
  1. Research: Sci-Hub provides access to nearly all scholarly literature

    Daniel S Himmelstein et al.
    The availability of almost all articles from toll access journals in the Sci-Hub repository will disrupt scholarly publishing towards more open models.
  2. Peer Review: Decisions, decisions

    Peter Rodgers
    Journals are exploring new approaches to peer review in order to reduce bias, increase transparency and respond to author preferences.
    1. Biochemistry and Chemical Biology
    2. Human Biology and Medicine

    Cancer: How does doxorubicin work?

    Anand G Patel, Scott H Kaufmann
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    1. Human Biology and Medicine

    Point of View: Strategies from UW-Madison for rescuing biomedical research in the US

    Judith Kimble et al.
    A cross-campus, cross-career stage and cross-disciplinary series of discussions at a large public university has produced a series of recommendations for addressing the problems confronting the biomedical research community in the US.
  3. Point of View: A recipe for mediocrity and disaster, in five axioms

    Henry R Bourne
    Biomedical research in the US will become unsustainable unless scientists and research institutions start to question certain assumptions they have long taken for granted.
    1. Neuroscience

    Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact

    Thomas A Ray et al.
    Selective synapse formation in a retinal motion-sensitive circuit is orchestrated by starburst amacrine cells, which use homotypic interactions to initiate formation of a dendritic scaffold that recruits projections from circuit partners.

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