5,773 results found
    1. Neuroscience

    The impact of pathological high-frequency oscillations on hippocampal network activity in rats with chronic epilepsy

    Laura A Ewell et al.
    A novel framework for separating normal and pathological high-frequency oscillations in animals with epilepsy uncovers new mechanisms for impaired hippocampal network function.
    1. Neuroscience

    Complexity of frequency receptive fields predicts tonotopic variability across species

    Quentin Gaucher et al.
    The A1 of ferrets and mice show similar tonotopic organizations, with neurons preferring a single frequency being more precisely organized into a tonotopic map than multipeaked neurons.
    1. Neuroscience

    Optogenetically induced low-frequency correlations impair perception

    Anirvan Nandy et al.
    Low-frequency correlations among neurons in monkey visual area V4 impair the animal's ability to perform an attention-demanding task, suggesting a causal role of these fluctuations in perception.
    1. Neuroscience

    The rate of transient beta frequency events predicts behavior across tasks and species

    Hyeyoung Shin et al.
    Across species, tasks and recording modalities, the rate of transient neocortical beta frequency (15-29Hz) events strongly predicts perceptual ability, providing fundamental mechanistic insight, with implications for tracking and manipulating brain dynamics.
    1. Neuroscience

    Hippocampal low-frequency stimulation prevents seizure generation in a mouse model of mesial temporal lobe epilepsy

    Enya Paschen et al.
    Optogenetic and electrical low-frequency stimulation in the sclerotic hippocampus prevents the emergence of spontaneous focal and evoked generalized seizures in a mouse epilepsy model.
    1. Evolutionary Biology

    Selection on mutators is not frequency-dependent

    Yevgeniy Raynes, Daniel Weinreich
    Contrary to intuition that the evolutionary fate of mutation rate modifying alleles is frequency-dependent, neither the strength nor the sign of selection on modifiers depends on initial frequency.
    1. Cell Biology
    2. Computational and Systems Biology

    Limits on information transduction through amplitude and frequency regulation of transcription factor activity

    Anders S Hansen, Erin K O'Shea
    The ability of cells to transmit information encoded in signaling dynamics is fundamentally limited by the gene decoding step.
    1. Neuroscience

    Cross-frequency synchronization connects networks of fast and slow oscillations during visual working memory maintenance

    Felix Siebenhühner et al.
    Cross-frequency synchronization of neuronal oscillations in visual and attentional brain systems predicts human working memory performance.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A variant-centric perspective on geographic patterns of human allele frequency variation

    Arjun Biddanda et al.
    New tools for visualizing population genetic data can provide a more direct understanding of levels of differentiation among human populations.
    1. Neuroscience

    Selective attenuation of Ether-a-go-go related K+ currents by endogenous acetylcholine reduces spike-frequency adaptation and network correlation

    Edward D Cui, Ben W Strowbridge
    Acetylcholine, a common modulator in the brain, controls spike-frequency adaptation by specifically attenuating Ether-a-go-go related K+ currents, thereby explaining many cortical network statistical changes often observed in vivo.

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