Simultaneous recordings of neural ensembles in both the frontal and parietal cortices reveal how persistent activity can be maintained in the primate brain during visuospatial working memory.

Prior experience alters content-specific neural representations of visual input in frontoparietal and default-mode networks.

In the human brain, default mode network BOLD deactivations can be accompanied by both increases and decreases in glucose metabolism, depending on the respective metabolic demands of task-positive cognitive control and attention networks.

Beta-band oscillations in the frontoparietal network may act as a filter of relevant versus irrelevant neural representations for the ongoing cognitive task.

Human intracranial electroencephalography recordings across 177 participants and four diverse episodic memory experiments demonstrate how the anterior insula node of the salience network orchestrates dynamics of large-scale brain networks.

Externally induced synchronous/desynchronous oscillations during working memory performance reveal distinct patterns of brain activity and connectivity across large-scale networks recruited by the task.

Neural correlates of somatosensory target detection are restricted to secondary somatosensory cortex, whereas activity in insular, cingulate, and motor regions reflects stimulus uncertainty and overt reports.

Dopaminergic medication has differential effects on the discovered electrophysiological networks, which could be used to develop new electrical and pharmacological interventions in Parkinson’s disease.

Loss of nonstationary connectivity in a subcortical fronto-temporoparietal network distinguishes patients with minimal conscious state and unresponsive wakefulness state, strongly supporting the mesocircuit hypothesis.

Structural network topology develops during adolescence to facilitate activation of the fronto-parietal executive system with lower theoretical energetic cost.