The cysteine pair oxidation state in nDsbD acts as a ‘switch’ controlling the presence or absence of frustration in the active-site and determining the dynamic behavior of the cap loop.

Allostery in an intrinsically disordered domain of glucocorticoid receptor is mediated by opposing thermodynamic signals that are directed through the production of different isoforms.

Nucleation, elasticity theory, and simulations were combined to construct a general phase diagram that elucidates the conditions for successful viral assembly and the key factors to prevent it.

A disordered region at the N-terminus of the glucocorticoid receptor can fine tune how cells respond to a hormone via an allosteric mechanism.

Recruiting PhD students can be a frustrating process, but Eve Marder looks forward to welcoming the latest crop in the autumn.

The spectacular frill around the neck of the lizard Chlamydosaurus has its origins in a mechanical instability that arises during development.

An over-emphasis on novelty is having detrimental effects on science.

A university genomics class provides detailed examples of how to design and execute Oxford Nanopore MinION hackathons as part of an academic curriculum.

Proposals to reduce the number of students who do PhDs are misguided because they would exclude young scientists with qualities that do not show up in exam results and interviews.