Dennis Segebarth, Matthias Griebel ... Robert Blum
A comparison of different bioimage analysis pipelines reveals how deep learning can be used for automatized and reliable analysis of fluorescent features in biological datasets.
The Mouse Action Recognition System is a computational pipeline for automated classification of social behaviors in freely interacting mice, accompanied by a graphical interface for analysis of multimodal neuroscience datasets.
Sara Calhoun, Magdalena Korczynska ... Andrej Sali
A computational method identifies the functions of orphan enzymes by organizing them into metabolic pathways; the prediction of a new l-gulonate catabolic pathway is experimentally tested and confirmed.
Alayne Cuzick, James Seager ... Kim E Hammond-Kosack
A framework has been devised that enables global participation in the curation of publications on any topic involving two or more living organisms, ranging from microscopic to larger sizes, in their natural or artificial environments or ecosystems.
A statistical model systematically associates functions of intrinsically disordered regions with sequence-distributed molecular features such as charge, residue composition, or repeat content.
Widespread, rapidly evolving disordered regions contain molecular features that are preserved over evolution and are associated with specific biological functions.