6,702 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A nanobody-based molecular toolkit provides new mechanistic insight into clathrin-coat initiation

    Linton M Traub
    New intracellularly-expressed llama anti-EPS15 nanobodies reveal that pioneer clathrin-coat components function upstream of AP-2 clathrin adaptor deposition at the plasma membrane.
    1. Cell Biology

    Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore

    Xun X Bao et al.
    Microtubule nucleation from the nuclear envelope in fission yeast involves repurposing of nuclear export proteins for a non-export-related function, docking cytoplasmic proteins at nuclear pore complexes.
    1. Developmental Biology
    2. Genetics and Genomics

    Neurogenesis: Silencing the alternative

    Priya Sivaramakrishnan, John Isaac Murray
    The transcription factor ztf-11 promotes neuronal differentiation by repressing other cell fates in the nematode worm C. elegans.
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    1. Neuroscience

    Amyotrophic Lateral Sclerosis: Marking the differences in motoneurons

    Simon A Sharples, Patrick J Whelan
    A subgroup of the neurons that control muscles becomes less excitable shortly before the symptoms of ALS develop.
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    1. Genetics and Genomics

    Neutral Evolution: The randomness that shapes our DNA

    Kelley Harris
    Just 5% of the human genome is subject to neutral evolution but this process remains central to understanding the history of human migration across the Earth.
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