Amyloid beta, the major component of plaques in Alzheimer's disease, acutely and reversibly signals to modulate sleep as a function of oligomeric length, independently of neuronal loss.

TcMAC21 is an appropriate “next gen” mouse model for DS research, and provides a proof of concept of using artificial chromosomes to generate non-mosaic humanized animal models of chromosome disorders.

The Bi-Genomic Mitochondrial-Split-GFP, where both fragments of the Split-GFP are expressed by separated translation machineries, shuts off cytosolic fluorescence of dual-localized proteins, allowing visualization of their mitochondrial echoforms.

Cancer systems immunology is a highly interdisciplinary field that is advancing our ability to understand and predict the complex behavior that orchestrates the interplay between tumors and the immune system.

MMnet is a conserved, trans-regulated gene network that controls skeletal homeostasis through osteoclast multinucleation and bone resorptive function.

A comprehensive, data-driven and interpretable nonlinear computational modeling framework based on deep neural networks uncovers different nonlinear transformations of speech signal in the human auditory cortex.

By combining ultra-high-field imaging with physiological and saliva measures it is established that interactions between locus coeruleus, hippocampus and amygdala vary along emotional memory stages, putatively reflecting distinct cognitive states.

Extinction and overexpectation lead to the same behavioural outcome, that is, reduction in learned fear, but engage different cortical areas.

Resident dermal Mφ are programmed locally, independently of bone-marrow monocytes during Staphylococcus aureus infection, leading to transiently increased resistance, which is limited by a decrease in macrophage life span.