Single-molecule immunoprecipitation method reveals that the high catalytic rate and multi-tasking capability make a concerted contribution to the strong signaling potency of the HER2-HER3 heterodimers.
Oscar Woolnough, Kiefer James Forseth ... Nitin Tandon
Direct insular recordings in humans reveal that contrary to several prominent models of speech production, it is not engaged in pre-articulatory planning, but in auditory and somatosensory components of speech.
Transcriptomes of cells in the Drosophila visual system combined with anatomy and other information reveal new functional insight into the visual circuit.
Shigehiro Namiki, Michael H Dickinson ... Gwyneth M Card
Systematic analysis of descending neuron anatomy reveals the basic functional map of descending sensory-motor pathways in flies and provides genetic tools for targeted interrogation of neural circuits.
Defects in synapse regeneration limit functional circuit recovery after nerve injury by misdirecting information via ectopic dendritic synapses, and also by functional and molecular deficits in reformed axonal synapses.
Xavier Guell, Jeremy D Schmahmann ... Satrajit S Ghosh
Cerebellar functional regions follow a gradual organization, which progresses from primary (motor) to transmodal (Default Mode Network) regions, and a secondary axis extends from task-unfocused to task-focused processing.
Sydney M Bailes, Daniel EP Gomez ... Laura D Lewis
The frequency content of resting-state fMRI signals contains information that can characterize and predict local variations in hemodynamic response timing which enhances the temporal precision of fMRI.
Benjamin W Okaty, Nikita Sturrock ... Susan M Dymecki
Dorsal raphe Pet1 neurons are molecularly heterogeneous, comprising as many as fourteen distinct subtypes that show biased cell body distributions across dorsal raphe subdomains.
The central complex, a highly conserved insect brain region important for navigation, is characterized by a high degree of recurrence and a sparseness of output pathways.