The primer extension and 5' flap processing activities of DNA polymerase I are physically coordinated by combined movements of the DNA substrate and the 5' nuclease domain of the enzyme.

ECM-Itgb1 signaling and cell-cell adhesion are pivotal and coordinate together to regulate pancreatic islet aggregation, architecture, and functional maturation during development.

Coordinated activation and deactivation of inhibitory neurons triggers sequential muscle contractions that enable fruit fly larvae to propel themselves backwards and forwards.

Impaired GABAergic and glutamatergic synaptic function and loss of interneurons in the amygdala, hippocampus, and cerebellum cause characteristic disease symptoms in a mouse model juvenile neuronal ceroid lipofuscinosis.

The role of genetically identified V3 interneurons with ascending propriospinal projections in the spinal locomotor circuitry and their contribution to the limb coordination and speed-dependent gait expression during locomotion were investigated using a combination of experimental studies and computational modeling.

Set1 has roles in chromatin organization and transcriptome control that are largely independent of histone H3 lysine 4 methylation.

Hemilineages link neuronal stem cells to behavioral functions by providing a conserved ground plan of neuronal types that evolution then uses to sculpt different types of walking and flight behaviors.

Conditional silencing of long ascending propriospinal neurons disrupts interlimb coordination of the fore and hindlimb pairs, but in a highly context-specific manner.

Cations are essential cofactors in the ATP activation mechanism of the KtrAB cation channel and appear to be cofactors of many other nucleotide-dependent RCK domains.

The structural and functional characterization of EleNRMT defines the basis for the distinct ion selectivity of a clade of the SLC11/NRAMP family which, instead of transporting transition metal ions, have evolved as uncoupled transporters of Mg²⁺.