7,585 results found
    1. Neuroscience

    Brain aging comprises many modes of structural and functional change with distinct genetic and biophysical associations

    Stephen M Smith et al.
    Imaging of structure and function in the brain from thousands of participants was used along with genetics and biophysical measures to study many different aspects of how the brain ages.
    1. Neuroscience

    Cortical tau deposition follows patterns of entorhinal functional connectivity in aging

    Jenna N Adams et al.
    Tau deposition in the aging brain follows patterns of functional connectivity that correspond to specific neural memory networks, and this relationship is strengthened in the presence of amyloid-β.
    1. Neuroscience

    Inter-individual differences in human brain structure and morphology link to variation in demographics and behavior

    Alberto Llera et al.
    Multi-modal structural data fusion questions the specificity of fMRI-behavior associations by providing strong evidence relating human brain structure to a wide range of behavioral measures previously associated to functional connectivity.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    In vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development

    Jia Zhao et al.
    In vivo imaging reveals that gradually increased amount of glucose mediates the heterogeneous functional development of individual β-cells by activating its major downstream calcineurin/NFAT signaling pathway.
    1. Cell Biology
    2. Computational and Systems Biology

    Removing physiological motion from intravital and clinical functional imaging data

    Sean C Warren et al.
    Image-based motion correction enables the use of fluorescence lifetime and other functional imaging modalities in an intravital and clinical context in the presence of physiological motion.
    1. Cell Biology
    2. Neuroscience

    Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain

    Ronit Ilouz et al.
    High-resolution, large-scale immunohistochemical mouse brain images showing global views of different brain regions, as well as cellular and subcellular details, identified distinct localization of PKA RIβ and RIIβ regulatory subunits that reveal functional differences.
    1. Neuroscience

    The heritability of multi-modal connectivity in human brain activity

    Giles L Colclough et al.
    Genes play an important role in determining the strength of functional connectivity in the human brain, and seem to outweigh the contribution from the developmental environment.
    1. Neuroscience

    Functional dissociation of stimulus intensity encoding and predictive coding of pain in the insula

    Stephan Geuter et al.
    Pain processing in certain brain regions implements predictive coding principles, offering a novel perspective on the neural basis of pain perception.
    1. Neuroscience

    Consolidation alters motor sequence-specific distributed representations

    Basile Pinsard et al.
    The consolidation of newly acquired motor skills induces a functional reorganization of sequential information representations within secondary motor cortex, basal ganglia and hippocampus.
    1. Neuroscience

    The relationship between spatial configuration and functional connectivity of brain regions

    Janine Diane Bijsterbosch et al.
    Connectivity network matrices, as estimated with masking or dual regression against group-level parcellations, reflect little or no unique cross-subject information that is not also captured by spatial topographical variability.

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