3,023 results found
    1. Cancer Biology
    Reproducibility Project

    Reproducibility Project: Cancer Biology

    Edited by Roger J Davis et al.
    Investigating reproducibility in preclinical cancer research.
  1. June 2015

    Episode 21: June 2015

    In this episode we hear about tinnitus and hyperacusis, salamanders, chemical harpoons, and the role of ultrasound and song in the mating rituals of mice and flies.
  2. May 2015

    Episode 20: May 2015

    In this episode we hear about echolocation, bacteriophages, babies and pain, a neural code for food abundance, and how zebrafish can make their own sunscreen.
  3. A syringe injecting a clear liquid into the Earth

    Episode 56: April 2019

    In this episode, we hear about multipartite viruses, brain maps of people without hands, measles vaccinations, reproducible science, and how to spot premature babies.
  4. Episode 47: May 2018

    In this episode, we hear about echolocation in bats, open science, a new use for aspirin, brain topography, and combining science and parenthood.
    1. Neuroscience

    TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte–tracheal interactions

    Zhiguo Ma, Marc R Freeman
    Astrocyte microdomain calcium transients are mediated by TrpML, stimulated by ROS and tyramine, and mediate astrocyte–tracheal interactions in CNS gas exchange.
    1. Neuroscience

    Spatial readout of visual looming in the central brain of Drosophila

    Mai M Morimoto et al.
    In the Drosophila central brain, synaptic connectivity extracts visual-spatial information from the axons of looming sensitive LC6 neurons that terminate in a glomerulus with minimal retinotopy.
    1. Cancer Biology

    TINF2 is a haploinsufficient tumor suppressor that limits telomere length

    Isabelle Schmutz et al.
    Mutations in TIN2, a component of shelterin that keeps telomere length in check, lead to cancer-predisposition by disabling the telomere tumor suppressor pathway.
    1. Developmental Biology

    Asymmetric neurogenic commitment of retinal progenitors involves Notch through the endocytic pathway

    Elisa Nerli et al.
    A quantitative live imaging approach unveils that earliest neurogenic progenitors in the vertebrate retina arise from asymmetric divisions and that this asymmetry involves Notch signalling through the endocytic pathway.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

    William Wan et al.
    Cryo-electron tomography reveals the structure and arrangement of the VP40 matrix protein lattice that mediates the formation of Ebola and Marburg virus particles.

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