18,385 results found
    1. Cell Biology
    2. Computational and Systems Biology

    CEM500K, a large-scale heterogeneous unlabeled cellular electron microscopy image dataset for deep learning

    Ryan Conrad, Kedar Narayan
    'Cellular Electron Microscopy 500,000 images' (CEM500K) is a highly heterogeneous, information-rich, non-redundant, unlabeled EM dataset curated to pre-train DL algorithms for better model generalization on EM segmentation tasks.
    1. Neuroscience

    Neuroelectrophysiology-compatible electrolytic lesioning

    Iliana E Bray, Stephen E Clarke ... Paul Nuyujukian
    Neuronal loss can be studied by passing electrical current through the same electrodes used for neuron measurement without disrupting recording ability.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Updates to the zoonotic niche map of Ebola virus disease in Africa

    David M Pigott, Anoushka I Millear ... Simon I Hay
    Building on previous work (Pigott et al. 2014), estimates of areas of potential transmission of Ebola virus are revised and updated to provide a contemporary map for use by researchers and policymakers.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Mapping global environmental suitability for Zika virus

    Jane P Messina, Moritz UG Kraemer ... Simon I Hay
    A global map of environmental suitability for Zika virus and the estimated population living at potential risk can help refine public health guidelines, travel advisories and intervention strategies at a crucial time in the global emergence of this arbovirus.
    1. Computational and Systems Biology
    2. Neuroscience

    Cell assemblies at multiple time scales with arbitrary lag constellations

    Eleonora Russo, Daniel Durstewitz
    A novel statistical algorithm for mining high-dimensional spike train (count) data for significant spatio-temporal patterns reveals new insights into task and brain area dependent functional organization of neural activity.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Integron activity accelerates the evolution of antibiotic resistance

    Célia Souque, José Antonio Escudero, R Craig MacLean
    Integrons deploy a variety of adaptive strategies including excision, shuffling, and duplication of cassettes that foster rapid bacterial adaptation and resistance evolution while protecting the genomic integrity of the host.
    1. Evolutionary Biology

    The layered costs and benefits of translational redundancy

    Parth K Raval, Wing Yui Ngan ... Deepa Agashe
    Manipulation of the E. coli translation machinery sheds new light on evolutionary constraints and optimization strategies for bacterial translation and growth.
    1. Developmental Biology

    Image3C, a multimodal image-based and label-independent integrative method for single-cell analysis

    Alice Accorsi, Andrew C Box ... Nicolas Rohner
    Image3C is a new image-based analysis of cell population composition for research organisms in which detailed cellular phenotypes are unknown or for which species-specific reagents are not available.
    1. Neuroscience

    Whole brain comparative anatomy using connectivity blueprints

    Rogier B Mars, Stamatios N Sotiropoulos ... Saad Jbabdi
    White matter connectivity assessed using diffusion MRI allows one to compare whole-brain organization between different animal species in a quantitative fashion, identifying homologous areas and regions of unique specialization.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Estimation and worldwide monitoring of the effective reproductive number of SARS-CoV-2

    Jana S Huisman, Jérémie Scire ... Tanja Stadler
    A new and throughly validated method for timely estimation of the effective reproductive number of SARS-CoV-2 aided in the public health response to the COVID-19 pandemic.

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