14 results found
    1. Cancer Biology

    Replication Study: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

    John Repass, Reproducibility Project: Cancer Biology
    Editors' Summary: This Replication Study did not reproduce those experiments in the original paper that it attempted to reproduce.
    1. Cancer Biology

    Registered report: Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

    John Repass, Nimet Maherali ... Reproducibility Project: Cancer Biology
    1. Cancer Biology

    Reproducibility in Cancer Biology: The who, where and how of fusobacteria and colon cancer

    Cynthia L Sears
    The association between the bacterium Fusobacterium nucleatum and human colon cancer is more complicated than it first appeared.
    Version of Record
    Insight
    1. Genetics and Genomics

    Associations of genetic and infectious risk factors with coronary heart disease

    Flavia Hodel, Zhi Ming Xu ... Jacques Fellay
    In a prospective, population-based cohort, high polygenic risk and infection with Fusobacterium nucleatum have a small, yet independent impact on coronary heart disease risk.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Consistent global structures of complex RNA states through multidimensional chemical mapping

    Clarence Yu Cheng, Fang-Chieh Chou ... Rhiju Das
    A multidimensional chemical mapping strategy enables confident determination of the structures of non-coding RNAs at 1-nm resolution, including previously intractable riboswitch and human regulon states.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Extensive transmission of microbes along the gastrointestinal tract

    Thomas SB Schmidt, Matthew R Hayward ... Peer Bork
    Microbial populations are continuous along the gastrointestinal tract, with increased transmission in colorectal cancer and rheumatoid arthritis patients.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Microbiome: Does disease start in the mouth, the gut or both?

    Andrei Prodan, Evgeni Levin, Max Nieuwdorp
    Oral bacteria colonize the gut more frequently than previously thought.
    Version of Record
    Insight
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Adjusting for age improves identification of gut microbiome alterations in multiple diseases

    Tarini S Ghosh, Mrinmoy Das ... Paul W O'Toole
    A multi-cohort analysis of 2,500 gut microbiomes and five major diseases discovers that disease-microbiome associations display specific age-centric trends, with diseases characterized by age-centric trends of species gain/loss.
  1. Annual Report: 2023 in review

    With the official launch of eLife’s new publishing model in January 2023, we look back on a year of activity supporting this alternative approach to research communication.
    1. Structural Biology and Molecular Biophysics

    Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter

    Parveen Goyal, KanagaVijayan Dhanabalan ... Subramanian Ramaswamy
    Revised
    Reviewed Preprint v2
    Updated

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