An accurate, robust, and lightweight technique for measuring eye movements in mice was developed using magnetic sensing, yielding the first high resolution recordings of eye movements in freely moving mice.
Single-cell RNA analysis of brain endothelium identifies the angiogenic venous capillary subset and respective resident endothelial progenitors at the origin of CCM lesions, while arterial endothelial cells are unaffected.
Experiments in a mouse model for Alzheimer’s disease using germ-free and conventionally housed animals reveal that microbiota-derived short-chain fatty acids promote the deposition of cerebral Aβ plaques.
Cell-based high-throughput screening identifies IBT21 as a chemical chaperone, that inhibits ER protein aggregation and prevents the cell death caused by a proteotoxin, the aggregation-prone prion protein.
VIP neurons are a novel class of inferior colliculus stellate neurons that project to long-range auditory and non-auditory targets and integrate inputs from the auditory brainstem and contralateral IC.