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The modulation of neural gain facilitates a transition between functional segregation and integration in the brain
James M Shine et al.
The flexible network architecture of the brain is sensitive to the modulation of neural gain, which may be mediated by ascending arousal nuclei, such as the noradrenergic locus coeruleus.
fMRI reveals neural activity overlap between adult and infant pain
Sezgi Goksan et al.
The newborn infant experience of pain closely resembles that observed in adults, suggesting that infants have the sensory and emotional capacity to experience pain.
Correction: Quantification of gait parameters in freely walking wild type and sensory deprived
César S Mendes et al.
Development: How do babies feel pain?
Manon Ranger, Ruth E Grunau
Different neuronal populations mediate inflammatory pain analgesia by exogenous and endogenous opioids
Xin-Yan Zhang et al.
Exogenous opioid analgesia is mediated by MORs expressed in glutamatergic neurons, whereas endogenous opioid analgesia is mediated by MORs expressed in GABAergic neurons.
Computational and Systems Biology
Olfactory receptor neurons use gain control and complementary kinetics to encode intermittent odorant stimuli
Srinivas Gorur-Shandilya et al.
Olfactory receptor neurons adapt to odorant mean and variance and use complementary kinetics to preserve the timing of odorant encounters, despite adaptation slowing down transduction.
Quantification of gait parameters in freely walking wild type and sensory deprived
César S Mendes et al.
Novel imaging experiments suggest that fruit flies modify their neural circuitry for walking at slow, medium and fast speeds, and that proprioception is not essential for coordinated walking.
Optical control of pain
with a photoactive mGlu
receptor negative allosteric modulator
Joan Font et al.
Localized drug photoactivation provides light-mediated analgesia in behaving mice.
Revealing a novel nociceptive network that links the subthalamic nucleus to pain processing
Arnaud Pautrat et al.
The subthalamic nucleus is linked to a nociceptive network and involved in nociceptive processing and perception.
Fabry Disease: Ion channels and neuropathic pain
Madeleine C Klein, Anne Louise Oaklander
Pain behaviors in a Fabry mouse model are associated with the accumulation of a fat molecule that disrupts sodium ion channels in small fiber neurons.
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