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A response regulator acquired via lateral gene transfer has rewired an ancestral genetic circuitry and regulates alternative pathogenic lifestyles.

Receptor recognition of antimicrobial peptides is important for Salmonellae to survive inside macrophages and cause disease.

A novel innate defense mechanism of cell lysis involves the coordinated oligomerization of a defensin by interaction with the membrane lipid, phosphatidylinositol 4,5-bisphosphate.

FMT alleviated the intestinal barrier damage caused by enterotoxigenic Escherichia coli infection in antibiotic-induced microbiome-disordered model through increasing the relative abundance of A. muciniphila in the intestine.

A multidisciplinary approach provides a description of the exocytic pathway that exports Salmonella Typhi's typhoid toxin from infected cells.

A horizontally shared type VI secretion system affects the interaction between vibrios and eukaryotic hosts.

A combination of simulations and experiments was used to discover druggable cryptic pockets in non-structural protein 1, a promising but difficult target for coronaviruses, indicating a viable drug discovery approach for otherwise undruggable targets.

The first overview of fitness interactions within a species provides information how genetic interactions and ecology combine together to determine trait evolution.

Vaccination activities that occurred before the COVID-19 pandemic, 2000-2019, are estimated to avert 50 million deaths, highlighting the enormous benefits of continued and improving vaccination.

Super-resolution microscopy reveals, at nanometric-scale, the highly organized protein structure of viroplasms, the viral factories used by rotavirus to replicate its genome and assemble new viral particles.