4,466 results found
    1. Neuroscience

    Neural activity in a hippocampus-like region of the teleost pallium is associated with active sensing and navigation

    Haleh Fotowat et al.
    Sparse firing in a hippocampus-like structure of the teleost telencephalon is linked to spatial navigation and active sensing.
    1. Cancer Biology
    2. Genetics and Genomics

    Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA

    Jin Xu et al.
    Epigenome and Mitochondrial Barcode of Lineage from Endogenous Mutations (EMBLEM) enable tracking cell lineage in combination with chromatin profile in ATAC-seq data.
    1. Computational and Systems Biology

    Essential metabolism for a minimal cell

    Marian Breuer et al.
    A near-complete flux balance analysis model of a minimal cell demonstrates the high essentiality of its metabolic genes, agrees well with experimental essentiality data and suggests some further gene removals.
    1. Cell Biology
    2. Developmental Biology

    Cytoskeletal tension and Bazooka tune interface geometry to ensure fusion fidelity and sheet integrity during dorsal closure

    Piyal Taru Das Gupta, Maithreyi Narasimha
    Restoration of molecular and morphological symmetry and mechanical integrity following epithelial fusion relies on adaptive changes that are mediated by cytoskeletal tension and Bazooka dependent modulation of fusing interface geometry.
    1. Cell Biology
    2. Computational and Systems Biology

    Saccharomyces cerevisiae goes through distinct metabolic phases during its replicative lifespan

    Simeon Leupold et al.
    With replicative age, S. cerevisiae shifts from a fermentative towards an unusual respiratory metabolism, accompanied by a decrease in growth and glucose uptake rate.
    1. Evolutionary Biology

    A Mesozoic clown beetle myrmecophile (Coleoptera: Histeridae)

    Yu-Lingzi Zhou et al.
    A 99-million year old beetle in amber was a myrmecophile—a social impostor of the earliest-known ant colonies—revealing the most ancient behavioral symbiosis yet discovered in the Metazoa.
    1. Neuroscience

    Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model

    Kevin P Koster et al.
    NMDA receptor function is regulated by protein depalmitoylation during visual cortical maturation and is dysfunctional in infantile neuronal ceroid lipofuscinosis.

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