1,926 results found
    1. Genetics and Genomics

    Passive and active DNA methylation and the interplay with genetic variation in gene regulation

    Maria Gutierrez-Arcelus et al.
    Detailed analysis of umbilical cord cells shows that the associations between DNA methylation, gene expression and genetic variation are complex and context-dependent.
    1. Plant Biology

    Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis

    Katherine Noelani Chang et al.
    The plant hormone ethylene regulates the expression of multiple genes in the model plant Arabidopsis, including those that respond to other hormones.
    1. Stem Cells and Regenerative Medicine
    2. Chromosomes and Gene Expression

    Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation

    Marc A Kerenyi et al.
    Lysine-specific demethylase 1 (Lsd1) has an essential role during both the early and later stages of blood cell development.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Evolutionary principles of modular gene regulation in yeasts

    Dawn A Thompson et al.
    The divergence of gene regulation during evolution in yeast traces phylogenetic distance with prominent changes being associated with changes in lifestyle and a whole genome duplication event.
    1. Plant Biology

    Plant Biology: When the time is ripe

    Siobhan M Brady
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    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    CAMKII and Calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16

    Li Tao et al.
    Longevity in C. elegans is influenced not only by insulin/IGF-1 signalling, but also by CAMKII and calcineurin, acting on the same target, the transcription factor DAF-16.
    1. Cell Biology
    2. Plant Biology

    Fluorescent sensors reporting the activity of ammonium transceptors in live cells

    Roberto De Michele et al.
    A modified form of Green Fluorescent Protein integrated into an ammonium transporter provides a sensor that can be used to monitor transport activity in vivo.
    1. Neuroscience

    A longitudinal study of Caenorhabditis elegans larvae reveals a novel locomotion switch, regulated by Gαs signaling

    Stanislav Nagy et al.
    C. elegans exhibits two distinct behavioural macro-states, active and quiet wakefulness, and protein kinase A regulates switching between these two states.
    1. Developmental Biology
    2. Genetics and Genomics

    The genome sequence of the colonial chordate, Botryllus schlosseri

    Ayelet Voskoboynik et al.
    The Botryllus schlosseri genome yields insights into the evolution of hematopoiesis.
    1. Cell Biology
    2. Developmental Biology

    Apical targeting of the formin Diaphanous in Drosophila tubular epithelia

    Tal Rousso et al.
    Synergistic interactions with PI(4,5)P2 and activated Rho1, which are enriched at the apical membrane of tubular organs, facilitate tight apical targeting of the formin Diaphanous.

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