50 results found
    1. Biochemistry and Chemical Biology

    Induction of Hepatitis B Core Protein Aggregation Targeting an Unconventional Binding Site

    Vladimir Khayenko, Cihan Makbul ... Hans M Maric
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Cell Biology

    Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance

    Atsushi Matsumoto, Akihito Inoko ... Junichi Ikenouchi
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Lipid discovery enabled by sequence statistics and machine learning

    Priya M Christensen, Jonathan Martin ... Kelli L Palmer
    A previously unknown lipid modification by a bacterial antibiotic resistance enzyme was identified through the analysis of a family of antibiotic resistance enzyme sequences with a machine learning approach.
    1. Neuroscience

    Attentional modulation of secondary somatosensory and visual thalamus of mice

    Gordon H Petty, Randy M Bruno
    Salient or behaviorally relevant stimuli, regardless of their modality, robustly activate both higher-order somatosensory and visual thalamic nuclei.
    1. Neuroscience

    A conserved code for anatomy: Neurons throughout the brain embed robust signatures of their anatomical location into spike trains

    Gemechu B Tolossa, Aidan M Schneider ... Keith B Hengen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology

    Disordered proteins interact with the chemical environment to tune their protective function during drying

    Shraddha KC, Kenny H Nguyen ... Thomas C Boothby
    The ability of intrinsically disordered proteins to protect sensitive enzymes during drying can be tuned through interactions with cosolutes.
    1. Neuroscience

    Robust optogenetic inhibition with red-light-sensitive anion-conducting channelrhodopsins

    Johannes Oppermann, Andrey Rozenberg ... Peter Hegemann
    Engineered anion-conducting channelrhodopsins with enhanced red-light sensitivity and accelerated kinetics enable precise, low-intensity optical silencing of neurons, advancing optogenetic control in neuroscience research.
    1. Neuroscience

    Neural basis of cognitive control signals in anterior cingulate cortex during delay discounting

    Jeremy K Seamans, Shelby White ... Christopher C Lapish
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Multi-day neuron tracking in high-density electrophysiology recordings using earth mover’s distance

    Augustine Xiaoran Yuan, Jennifer Colonell ... Timothy D Harris
    Neurons can be tracked in mice implanted with Neuropixels 2.0 probes for up to 8 weeks using visual receptive fields to score tracking in the absence of reference data.
    1. Neuroscience

    Repix: reliable, reusable, versatile chronic Neuropixels implants using minimal components

    Mattias Horan, Daniel Regester ... Yoh Isogai
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete

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