GapR-seq enables the global mapping of positive supercoiling in bacteria and yeast, revealing positive supercoils downstream of highly expressed genes and, in yeast, associated with centromeres, pericentromeres, telomeres, replication origins, and R-loops.

A gene network analysis approach reveals a conserved small regulatory RNA that is crucial for bacterial cell survival across distinct stress conditions.

A statistically principled approach developed to estimate phase of rhythmic signals in real-time shows robustness to multiple sources of error and also provides confidence criteria.

When behavioral outcomes are unfavorable, the brain searches for better outcomes by deliberately increasing its internal variability.

Using barcoded mutagenesis and a high-throughput genetic screen results in the identification of 150 genes that affect lipid accumulation in a non-model yeast system.

The NDNF-like factor Nord is a Hedgehog-induced and extracellular-localized dosage-dependent BMP modulator that regulates Drosophila wing patterning and growth.

The ability of intrinsically disordered proteins to protect sensitive enzymes during drying can be tuned through interactions with cosolutes.