661 results found
    1. Computational and Systems Biology
    2. Neuroscience

    The interpretation of computational model parameters depends on the context

    Maria Katharina Eckstein, Sarah L Master ... Anne GE Collins
    Context factors such as experimental task and model parameterization can significantly impact modeling results, such that across tasks, the same participants show different fitted parameter values, and parameters capture different cognitive processes across tasks.
    1. Neuroscience

    Neuroscout, a unified platform for generalizable and reproducible fMRI research

    Alejandro de la Vega, Roberta Rocca ... Tal Yarkoni
    A web-based analysis platform for public fMRI data using naturalistic stimuli, leveraging state-of-the-art feature extraction models to enable more generalizable and reproducible findings.
    1. Computational and Systems Biology
    2. Neuroscience

    A generalizable brain extraction net (BEN) for multimodal MRI data from rodents, nonhuman primates, and humans

    Ziqi Yu, Xiaoyang Han ... Jianfeng Feng
    The Brain Extraction Network (BEN) provides a robust, accurate, and generalizable solution not only for extracting brain tissue from multimodal MRI data in rodents, non-human primates, and humans, but also for improving the accuracy of downstream neuroimaging processing tasks.
    1. Neuroscience

    Enhancing precision in human neuroscience

    Stephan Nebe, Mario Reutter ... Gordon B Feld
    Measurement precision offers a comprehensive perspective on good scientific practices to improve reproducibility of research results by providing means to optimize design and analysis parameters (e.g. sample size, trial count, or sample heterogeneity) in accordance with the researcher’s goals.
    1. Neuroscience

    Neural precursors of decisions that matter—an ERP study of deliberate and arbitrary choice

    Uri Maoz, Gideon Yaffe ... Liad Mudrik
    The readiness potential—a long-established neural precursor of voluntary action claimed to precede the onset of the conscious decision to move—is absent, or at least significantly reduced, for deliberate decisions.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes

    Megan E Carey, Zoe A Dyson ... Global Typhoid Genomics Consortium Group Authorship
    An analysis of the largest Salmonella Typhi genome collection to date (n=13,000) provides an updated overview of global genome diversity and antimicrobial resistance trends over time to inform public health action.
    1. Neuroscience

    Somatic and vicarious pain are represented by dissociable multivariate brain patterns

    Anjali Krishnan, Choong-Wan Woo ... Tor D Wager
    Understanding others' pain is grounded in cognitive rather than sensory faculties.
    1. Ecology
    2. Evolutionary Biology

    Ecological and social pressures interfere with homeostatic sleep regulation in the wild

    J Carter Loftus, Roi Harel ... Margaret C Crofoot
    Collective dynamics and site familiarity, but not the recent history of sleep and activity, shape sleep patterns in a wild social primate.
    1. Neuroscience

    Characterizing a psychiatric symptom dimension related to deficits in goal-directed control

    Claire M Gillan, Michal Kosinski ... Nathaniel D Daw
    A dimensional approach to psychiatry demonstrates the specificity and generalizability of a neurocognitive marker of compulsive behavior and intrusive thought via large-scale online testing.
    1. Computational and Systems Biology

    Quantifying dynamic facial expressions under naturalistic conditions

    Jayson Jeganathan, Megan Campbell ... Michael Breakspear
    A novel computational pipeline uses time-frequency analysis to capture the dynamics of human facial expressions, and demonstrates abnormal facial dynamics in melancholic depression.

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