368 results found
    1. Neuroscience

    A generative model of electrophysiological brain responses to stimulation

    Diego Vidaurre
    Genephys is a generative model for dissecting the different aspects that compound our neural responses to perceptual stimulation, identifying which aspects remain stable and which ones vary across experimental repetitions.
    1. Computational and Systems Biology
    2. Neuroscience

    A simple generative model of the mouse mesoscale connectome

    Sid Henriksen, Rich Pang, Mark Wronkiewicz
    A realistic model of the connections between local populations of neurons in the adult mouse brain can be constructed based on just two biologically plausible rules.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Distinguishing different modes of growth using single-cell data

    Prathitha Kar, Sriram Tiruvadi-Krishnan ... Ariel Amir
    Single-cell data analysis must be guided by an underlying model.
    1. Neuroscience

    Neural assemblies uncovered by generative modeling explain whole-brain activity statistics and reflect structural connectivity

    Thijs L van der Plas, Jérôme Tubiana ... Georges Debrégeas
    A data-driven network model offers an interpretable and physiologically sound description of the whole-brain spontaneous neural activity of zebrafish larvae.
    1. Neuroscience

    A dynamic generative model can extract interpretable oscillatory components from multichannel neurophysiological recordings

    Proloy Das, Mingjian He, Patrick L Purdon
    Oscillation component analysis enables cognitive neuroscientists to summarize millisecond-precision high-dimensional neurophysiological recordings into a smaller set of oscillatory components through biophysically inspired generative modeling of neural oscillations.
    1. Computational and Systems Biology

    Generative power of a protein language model trained on multiple sequence alignments

    Damiano Sgarbossa, Umberto Lupo, Anne-Florence Bitbol
    An iterative procedure using language models allows the generation of sequences from protein families, which score similarly to natural and experimentally validated sequences, with particular promise for small families.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Deep generative models for T cell receptor protein sequences

    Kristian Davidsen, Branden J Olson ... Frederick A Matsen IV
    Deep learning improves estimation of T cell receptor cohort frequencies and learns the rules of VDJ recombination, potentially making it helpful for vaccine design.
    1. Neuroscience

    Toward a more informative representation of the fetal–neonatal brain connectome using variational autoencoder

    Jung-Hoon Kim, Josepheen De Asis-Cruz ... Catherine Limperopoulos
    A nonlinear deep generative model can represent fetal–neonatal resting-state functional magnetic resonance imaging better than conventional linear models.
    1. Neuroscience

    Likelihood approximation networks (LANs) for fast inference of simulation models in cognitive neuroscience

    Alexander Fengler, Lakshmi N Govindarajan ... Michael J Frank
    A novel method and software provides researchers with the capability to rapidly, flexibly, and robustly perform Bayesian parameter estimation of theoretically meaningful models in cognitive neuroscience that were heretofore intractable.
    1. Neuroscience

    Bayesian analysis of phase data in EEG and MEG

    Sydney Dimmock, Cian O'Donnell, Conor Houghton
    A Bayesian model of phase angles illustrates a novel approach to the analysis of phase coherence in frequency-tagged experiments.

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