Browse the search results

A system genetics approach reveals a unique molecular signature of non-alcoholic fatty liver disease in mice and identifies novel genetic factors affecting hepatic steatosis.

Heritable variation in the benefit maize plants receive from arbuscular mycorrhizal fungi supports the feasibility of breeding crops to optimize use of this ancient symbiosis.

A genome-wide association study using whole-genome sequencing data identifies the first known susceptibility genes for posterior urethral valves, the most common cause of kidney failure in boys, implicating the transcription factor TBX5 and planar cell polarity gene PTK7.

The discovery of three distinct and independent trans-regulating genomic loci influencing heart mass using a well-characterized mouse reference population provides evidence in support of the hypothesis that genetic diversity in the mitochondrial proteome plays a critical role in heart pathophysiology.

A combination of genetics, experimental evolution and mathematical modelling defines information necessary to predict the outcome of short-term adaptive evolution.

Genome wide association analyses in a wild-derived Drosophila melanogaster population uncover extensive variation in cuticular hydrocarbon composition, which may present a target for natural selection and adaptive evolution.

Genome-wide association studies on a diallel yeast panel revealed the relevance of low-frequency variants on the phenotypic diversity and consequently on the missing heritability at a population-scale.

Although cellular organelles show a functional deterioration in aging, genetic loci associated with common age-associated disease instead nominate nuclear transcription factors across several age-related diseases.

A genome editing resource for discovering, in Drosophila, the organization of cellular structure and function by phosphoinositide signaling.