Meiosis and differentiation of basidium, a defining sexual structure of the phylum Basidiomycota, are genetically integrated by a shared regulatory program to ensure the formation of infectious meiospores in Cryptococcus neoformans.

A genetic selection of toxicity suppressors coupled to high-throughput sequencing has captured metastable RNA structures that co-transcriptionally inhibit the translation of a bacterial toxin.

Ts65dn mice exhibit structural, functional, molecular, and genetic alterations that are modulated but unrecovered by prenatal chronic GTE-EGCG, highlighting the importance of holistic studies to understand complex disorders and treatments.

Imaging of structure and function in the brain from thousands of participants was used along with genetics and biophysical measures to study many different aspects of how the brain ages.

Convergent transcription and stalling of transcription are enriched at DNA breakpoints found in acute lymphoblastic leukemia and associate with DNA structures and sequences that mediate genetic instability.

Random sequence RNA pools display an innate capacity for ligation and recombination, enabling them to “bootstrap” themselves towards higher compositional, informational and structural complexity.

Cationic cell-penetrating peptides (CPPs) enter cells through ~2 (–5)-nm-wide water pores induced by the strong negative plasma membrane potential that CPPs and the activity of potassium channels generate.

A generalizable approach to understanding the logic of molecular recognition reveals the contributions of individual residues to the specificity of protein-protein interactions.

Genetic variants interact with open chromatin to alter gene expression within topologically associated domains of DNA in outbred mice.

It is always better to use mixed effects models over principal components association regression for genetic association studies of continuous traits, since the former models family structure and close relatives are always found in real human studies.